Hiroxine Tablet 100 mg (Levofloxacin Hydrate)

Adult dose

Typically, adults take 100 mg of levofloxacin orally 2 to 3 times a day. In severe cases or insufficient effectiveness, the dose can be increased to 200 mg, 3 times a day. Adjustments may be made based on age and symptoms.

This medicine is a fluoroquinolone antibiotic used for the treatment of bacterial infections. However, it can cause serious side effects such as tendinitis, tendon rupture, peripheral neuropathy, central nervous system disorders, and exacerbation of myasthenia gravis, so caution is needed. If such side effects occur, the medication should be discontinued immediately, and it should not be administered to patients with myasthenia gravis. Also, it should be used only when there are no other treatment options for certain infections such as acute bacterial rhinosinusitis, acute exacerbations of chronic bronchitis, uncomplicated urinary tract infections, and acute otitis media. The risk of tendon rupture is increased in elderly patients, patients with renal impairment, solid organ transplant recipients, and patients receiving corticosteroids; therefore, it should not be used in combination with corticosteroids. This medicine may increase the risk of seizures, so it should be used cautiously in patients with epilepsy or central nervous system disorders. Various side effects may occur, including hypersensitivity reactions, severe allergic reactions, neuropsychiatric symptoms (such as anxiety, depression, hallucinations), arrhythmias, renal and hepatic dysfunction, blood abnormalities, gastrointestinal disturbances, musculoskeletal disorders, and skin reactions; thus, any unusual symptoms should be reported to a healthcare professional immediately. Notably, severe skin reactions and aortic aneurysms, as well as valvular heart disease, may occur, so careful observation is required. This medicine may have reduced absorption if taken with certain antacids or medications that contain iron, calcium, etc., so intervals between doses should be maintained. Additionally, combined use with blood glucose control medications may result in blood glucose fluctuations, so careful monitoring of blood glucose levels is necessary. Pregnant or nursing women, growing adolescents under 18 years of age, patients with a history of hypersensitivity to this medicine or quinolone antibiotics should not take this medicine. Elderly patients may experience elevated drug concentrations due to renal function impairment, so careful monitoring of dosage adjustments and the occurrence of side effects is necessary. In case of overdose, central nervous system symptoms and cardiac abnormalities may appear; thus, appropriate treatment should be sought immediately at a medical institution. During the course of treatment with this medicine, strong sunlight or artificial ultraviolet exposure should be avoided, and caution should be exercised while driving or operating machinery if dizziness or drowsiness is experienced.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweating, pallor, severe rash with fever, blisters, skin desquamation, pain in oral/ocular mucous membranes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), extreme drowsiness, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Nausea
• diarrhea
• vaginitis
• insomnia
• abdominal pain
• bloating
• itching
• dizziness
• rash
• dyspepsia

This medicine should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius, which helps preserve its effectiveness and prevent deterioration.

Appearance

White to off-white, round, film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle