Aprogen Rabeprazole Tablet 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcer and duodenal ulcer: Take 10 mg orally once daily or 20 mg once daily as needed. Typically, gastric ulcers are treated for up to 8 weeks, and duodenal ulcers for up to 6 weeks. For erosive or ulcerative gastroesophageal reflux disease: Take 10 mg or 20 mg once daily for 4 to 8 weeks. If symptoms do not improve after 8 weeks, an additional 8 weeks at 10 mg or 20 mg twice daily may be administered.

This medication should not be used in patients with allergies to certain components or benzimidazoles. Patients allergic to penicillin group or macrolide antibiotics should also be cautious when using this medication. Patients taking certain heart-related medications or those on atazanavir or rilpivirine should avoid using this medication. Pregnant or breastfeeding women should not take this medication. Patients with impaired liver function and the elderly should use this medication cautiously, and those with a history of drug allergies should also take precautions. This medication may cause allergic reactions such as skin rash, itching, or hives; if symptoms occur, discontinue use. Regular monitoring is needed as there may be risks of decreased blood cell counts, liver function abnormalities, heart and vascular issues, and gastrointestinal symptoms. Various neurological and respiratory symptoms such as headache, dizziness, insomnia, cough, and muscle pain have also been reported; consult a doctor if unusual symptoms occur. Long-term use may increase the risk of osteoporosis and fractures, hence caution is advised, and hypomagnesemia may rarely occur; thus, it is advisable to monitor serum magnesium levels. This medication suppresses gastric acid secretion, which may slightly elevate the risk of bacterial infections in the gastrointestinal tract; inform healthcare providers if diarrhea persists. Caution is advised when driving or operating machinery due to potential drowsiness. Drug interactions may occur, so inform your healthcare provider about any other medications you are taking, especially antibiotics or blood coagulation-affecting medications. Safety during pregnancy has not been established; therefore, it should not be used, and it is also recommended not to take while breastfeeding. In the elderly, adverse reactions may be more pronounced due to impaired liver function, so usage should be adjusted or discontinued if symptoms arise. Safety in children has not been sufficiently established, so it is advisable not to use. In case of overdose, there is no specific antidote, and appropriate treatment should be given according to symptoms; swallow the tablets whole without chewing or breaking them. Keep this medication out of reach of children and do not transfer it to another container for safety. Long-term use of this medication may exacerbate some autoimmune diseases; if related symptoms appear, consult a specialist immediately. Furthermore, it may affect the results of certain diagnostic tests due to decreased gastric acidity, hence it is preferable to temporarily discontinue use before testing.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, fulminant hepatitis, liver dysfunction, jaundice, severe skin reactions (toxic epidermal necrolysis, mucosal membrane syndrome, Stevens-Johnson syndrome), asthma attacks, dyspnea, pulmonary embolism, interstitial pneumonia, acute interstitial nephritis, sudden and very severe headache, seizures, confusion, vision disturbances, paralysis, severe edema, increased blood pressure, vascular complications

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechial hemorrhage

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. It is advisable to maintain a storage temperature between 1 to 30 degrees Celsius. This will help preserve the medication's effectiveness for a long time.

Appearance

Pale yellow round enteric-coated tablet

Package unit

(For domestic use) 28 tablets/PTP (28 tablets/PTP x 1), (For export) 28 tablets/PTP (14 tablets/PTP x 2)