Medication info
Alpirebofloxacin Tablets 100 mg (Levofloxacin Hemihydrate)

Alpirebofloxacin Tablets 100 mg (Levofloxacin Hemihydrate)

Prescription medicationTablet경구
Ingredient · strength
Levofloxacin Hydrate›100mg / 1 tablet
Manufacturer / importer
(주)알피바이오
Appearance
Pale yellow round film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 201403186 · Approved 2014.07.16 · Insurance code 661604410

Summary

Main use
Treatment of complex skin and soft tissue infections and secondary infections of chronic respiratory diseases
Who takes it
Adults
Adult dose
Typically, for adults, levofloxacin is administered orally at a dose of 100 mg 2 to 3 times daily. For severe or inadequately responsive patients, a dose of 200 mg 3 times a day may be used. Adjustments can be made according to age and symptoms.

Ingredients

Manufacturer
(주)알피바이오

Efficacy & effects

Treatment of complex skin and soft tissue infections and secondary infections of chronic respiratory diseases

  • Complex skin infections
  • soft tissue infections
  • chronic bronchitis
  • diffuse bronchiectasis
  • secondary infections of chronic respiratory diseases
  • community-acquired pneumonia
  • bronchiectasis infections
  • acute pyelonephritis
  • cystitis
  • prostatitis
  • gonococcal urethritis
  • non-gonococcal urethritis
View approved original text

This medication is effective against various bacteria such as Staphylococcus, Streptococcus, Pneumococcus, Neisseria gonorrhoeae, and Escherichia coli, and is used for skin and soft tissue infections, respiratory infections such as chronic bronchitis or pneumonia, and urinary tract infections including acute pyelonephritis and cystitis. It also helps treat various infections including bacterial dysentery, gastroenteritis, female reproductive tract infections, ophthalmic infections such as eyelid inflammation, otitis media, sinusitis, periodontal disease, and cholecystitis. However, as a fluoroquinolone antibiotic, there is a potential for severe adverse reactions, so it should only be used when there are no alternative treatments for specific infections. In summary, this medication is used to treat various infections caused by multiple bacteria, helping to aid patient recovery.

How to take

Adult dose

Typically, for adults, levofloxacin is administered orally at a dose of 100 mg 2 to 3 times daily. For severe or inadequately responsive patients, a dose of 200 mg 3 times a day may be used. Adjustments can be made according to age and symptoms.

Precautions

This medication is a fluoroquinolone antibiotic used for the treatment of specific bacterial infections. While taking this medication, tendon-related issues such as tendonitis or tendon rupture may occur, so discontinue use immediately if there is pain or inflammation in the tendons. Peripheral neuropathy and central nervous system symptoms (dizziness, anxiety, seizures, etc.) may also occur, so caution is advised, and you should consult a physician immediately if these symptoms appear. Patients with myasthenia gravis should not use this medication, as it may worsen their symptoms. This medication is not administered to children or adolescents under 18 years of age, pregnant or breastfeeding women, or individuals with epilepsy. Elderly patients or those with impaired renal function may have increased concentrations of this medication, so dose adjustment and caution are necessary. When taken with certain antacids, iron supplements, or calcium supplements, absorption may be decreased, so dosing intervals should be spaced out. Caution is necessary when taken with non-steroidal anti-inflammatory drugs or theophylline as it may increase the risk of seizures. Diabetic patients taking blood sugar control medications may experience fluctuations in blood sugar, so blood sugar should be checked frequently. Photosensitivity reactions may occur, so avoid exposure to strong sunlight or artificial ultraviolet light, and discontinue use if a rash or blisters develop. If dizziness, drowsiness, or visual disturbances occur during medication use, avoid driving or operating machinery. Severe allergic reactions, liver or kidney function abnormalities, blood abnormalities, and heart rhythm irregularities may occur, so report any unusual symptoms to medical personnel immediately for appropriate action. In case of overdose, central nervous system symptoms and cardiac abnormalities may appear, so seek medical treatment immediately.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, high fever accompanied by severe rash, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory symptoms accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, and liver abnormalities (jaundice). Sudden and severe headaches.

Mild side effects

Nausea, diarrhea, vaginitis, insomnia, abdominal pain, bloating, itching, dizziness, rash, dyspepsia, stomatitis, glossitis, dry mouth, constipation, vomiting, fungal infections, genital itching, headache, neurosis, erythematous rash, urticaria, decreased appetite, drowsiness, agitation, thirst, tremors, allergic reactions, palpitations, elevated BUN and serum creatinine, and elevated hepatic enzyme levels (AST/ALT), ALP, γ-GTP, total bilirubin.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. It is best to maintain storage temperatures between 1 to 30 degrees Celsius. This helps to preserve the effectiveness and safety of the medication for a prolonged period.

Appearance and packaging

Appearance

Pale yellow round film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.