Colestop Tablet 10mg (Rosuvastatin Calcium)

Adult dose

It can be administered at any time of the day, irrespective of meals. The initial dose is 5 mg once daily, and if more significant reductions in LDL-cholesterol are needed, the maintenance dose can be adjusted accordingly. Most patients are controlled at a maintenance dose of 10 mg once daily. The dosage should be appropriately adjusted every 4 weeks or longer based on LDL-cholesterol levels, treatment goals, and patient response.

Child dose

The usual dosage range for pediatric patients aged 10 to 17 years is 5 mg to 20 mg once daily. The dosing should be adjusted based on individual treatment goals for each patient, with adjustments made every 4 weeks or longer.

This medication may not be suitable for certain patients. For instance, it should not be administered to patients who have had allergic reactions to this medication, those with severe liver dysfunction, patients with muscle diseases, or individuals with severe kidney impairment. Additionally, special caution is needed for pregnant or breastfeeding women, and fertile women who are not using effective contraception. This medication may increase the risk of muscle-related side effects; therefore, if symptoms like muscle pain or weakness occur, the healthcare provider should be notified immediately. It may affect liver function, so patients with a history of liver disease or excessive alcohol consumption require regular liver function tests. Attention should be paid to drug interactions while taking this medication, especially when used concurrently with certain antibiotics, antifungal agents, immunosuppressants, etc., as the risk of muscle damage may increase. Kidney function tests are recommended during high-dose administration, and Asian patients may require dose adjustments due to higher drug concentrations. If severe skin reactions or allergy symptoms occur while taking this medication, it should be discontinued immediately and the healthcare provider consulted. Women who could become pregnant should take care not to become pregnant while on this medication and should discontinue it immediately if pregnancy occurs. No specific antidote exists for overdose, thus treatment should be symptomatic and include liver and muscle function tests. Finally, this medication may cause dizziness; caution is advised while driving or operating machinery.

Serious side effects

Allergic reactions including hives and angioedema, pancreatitis, myopathy (including myositis), rhabdomyolysis, polyneuropathy, peripheral neuropathy, severe muscle weakness, shortness of breath, ophthalmoplegia, thrombocytopenia, jaundice, hepatitis, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, edema, fatal and non-fatal liver failure, acute renal failure

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• muscle pain
• weakness
• hematuria

This medication should be stored in a tightly sealed container to prevent air or moisture ingress, at room temperature between 1 degree and 30 degrees. Proper storage will help maintain the drug’s effectiveness for a longer period.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle