Doxy Tablet (Doxycycline Hydrate)

Adult dose

Adults: The initial dose of doxycycline is 100 mg (potency) orally every 12 hours. The maintenance dose is 100 mg (potency) per day in 1 ∼ 2 divided doses. For severe infections, administer the initial dose every 12 hours. This medicine should be continued for 24 ～ 48 hours after symptoms have subsided and the fever has resolved. For streptococcal infections, continue treatment for at least 10 days to prevent the onset of rheumatic fever or glomerulonephritis. Adjust the dose as appropriate according to age and symptoms.

Child dose

Adolescents aged 12 years or older weighing 45 kg or less: The initial dose is 4 mg (potency) per kg of body weight per day, given orally in 2 divided doses. The maintenance dose is 2 mg (potency) per kg of body weight per day in 1 ∼ 2 divided doses. Adolescents aged 12 years or older weighing more than 45 kg: Administer the adult dose.

This medication may cause severe diarrhea and colitis due to a bacterium called Clostridium difficile. If such symptoms appear, immediate consultation with healthcare personnel is necessary, and careful observation is required for more than 2 months following treatment. Moreover, there may be serious skin reactions during the course of this medication; thus, if any skin abnormality arises, the medication should be stopped immediately and treatment should be sought. This medication should not be used in individuals with allergies to it or similar components, in pregnant or nursing women, in children under 12 years of age, in patients with severely impaired kidney or liver function, or in patients taking specific drugs. Patients with reduced kidney function require dosage adjustment and serum concentration monitoring, and excessive exposure to sunlight may result in serious skin reactions. Caution is also required for patients with liver dysfunction, esophageal disorders, the elderly, and those with allergic tendencies. This medication may interact with various drugs; therefore, it is essential to inform healthcare personnel if you are taking other medications. Pregnant or potentially pregnant women should not use this medication, and nursing should be stopped if this medication is being taken while breastfeeding. It is advisable not to use this medication in children under 12 years of age due to risks of tooth discoloration and bone growth disorders. The elderly should start with a low dose due to the risk of impaired kidney function and bleeding and should be monitored closely. During the use of this medication, it should be taken either sitting or standing with plenty of water to reduce the risk of esophageal irritation and ulcer, and if gastrointestinal disturbances occur, it is recommended to take it with food. In case of overdose, medication should be stopped immediately and appropriate treatment should be sought at a medical institution.

Diarrhea, colitis, exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, hemolytic anemia, neutropenia, thrombocytopenia, hypersensitivity, anaphylactic shock, angioedema, exacerbation of systemic lupus erythematosus, pericarditis, serum sickness, hypotension, dyspnea, tachycardia, peripheral edema, urticaria, microscopic brown discoloration of the thyroid gland, decreased appetite, headache, benign intracranial hypertension, protrusion of the numbers, tinnitus, flushing, nausea, vomiting, dyspepsia, pancreatitis, membranous colitis, esophageal ulcer, esophagitis, enterocolitis, inflammation around the anal-genital region, dysphagia, abdominal pain, glossitis, tooth discoloration, hepatotoxicity, hepatitis, liver dysfunction, photosensitive reaction, rash, exfoliative dermatitis, photo-onycholysis, arthralgia, myalgia, increased BUN, anemia, decreased granulocytes, atypical lymphocytes, decreased lymphocytes, lymphadenopathy, blood coagulation disorders, anaphylactic reaction, fever, sensory disturbances, anxiety, restlessness, severe colitis with bloody stool, loose stools, stomatitis, sore throat, black hairy tongue, hoarseness, jaundice, onycholysis, nail color changes, fixed drug eruption, arthritis, kidney damage, interstitial nephritis, acute renal failure, oliguria, hematuria, visual impairment, optic disc edema, reduced and lost sense of smell and taste, vitamin K deficiency, vitamin B complex deficiency symptoms, facial tongue and laryngeal edema, yellow urine, reduced urinary sugar, liver and kidney parenchymal damage, anaphylactic reaction, liver damage, esophagitis, esophageal ulcer, hypersensitivity reaction

This medication is sensitive to air and light; it should be stored in a tightly sealed container. Additionally, it is important to maintain a temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

Yellow round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle