Medication info
Uronast 10mg (Propiverine Hydrochloride)

Uronast 10mg (Propiverine Hydrochloride)

Prescription medicationTabletOral
Ingredient · strength
Propiverine Hydrochloride›10mg / 1 tablet
Manufacturer / importer
Myeongmun Pharmaceuticals Co., Ltd.
Appearance
White round film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201402986 · Approved 2014.07.07 · Insurance code 649806610

Summary

Main use
Relief of symptoms of overactive bladder and urinary frequency and incontinence due to bladder disorders
Who takes it
Adults
Adult dose
Adults: Administer 20 mg of propiverine hydrochloride orally once daily after a meal. The dose may be adjusted according to symptoms; if the effect is inadequate and there are no safety concerns, 20 mg may be taken up to twice daily.

Ingredients

Manufacturer
Myeongmun Pharmaceuticals Co., Ltd.

Efficacy & effects

Relief of symptoms of overactive bladder and urinary frequency and incontinence due to bladder disorders

  • Frequent urination
  • incontinence
  • neurogenic bladder
  • neurogenic frequency
  • unstable bladder
  • bladder irritation
  • chronic cystitis
  • chronic prostatitis
  • urgency of urination
  • urge incontinence
View approved original text

This medication treats urinary frequency and incontinence caused by conditions such as neurogenic bladder, neurogenic frequency, unstable bladder, chronic cystitis, and chronic prostatitis which result in bladder irritation. It is also used to relieve the urgency of urination, frequency, and urge incontinence associated with overactive bladder. This drug improves symptoms by suppressing excessive contractions of the bladder. Therefore, it helps to effectively manage bladder-related symptoms and improves quality of life. It is important for patients to continue taking this medication for symptom relief. This drug is used for the treatment of these bladder conditions.

How to take

Adult dose

Adults: Administer 20 mg of propiverine hydrochloride orally once daily after a meal. The dose may be adjusted according to symptoms; if the effect is inadequate and there are no safety concerns, 20 mg may be taken up to twice daily.

Precautions

This medication should not be used in certain patients. It should not be administered to patients who have allergies to this drug or its components, have gastrointestinal obstruction, or have impaired gastrointestinal motility, as it may worsen symptoms. Additionally, it should not be used by patients with urinary retention, angle-closure glaucoma, myasthenia gravis, serious heart disease, liver dysfunction, or history of arrhythmia. Patients with genetic issues such as lactose intolerance should also exercise caution. This medication should be administered cautiously in patients with urinary difficulty, liver impairment, kidney impairment, Parkinson's disease, and hyperthyroidism. Caution is also needed for elderly patients or those with autonomic neuropathy, coronary artery disease, congestive heart failure, or glaucoma when using this drug. When taking this medication, serious side effects such as psychiatric symptoms, severe constipation or abdominal distension, irregular heartbeat, thrombocytopenia, kidney dysfunction, skin rash, acute glaucoma attacks, liver dysfunction, myalgia may occur, and if symptoms arise, it is essential to immediately discontinue use and consult a physician. Moreover, due to similar diseases and symptoms with bladder cancer or prostate cancer, this medication should only be used after a definitive diagnosis, and patients with lower urinary obstruction diseases such as benign prostatic hyperplasia should prioritize treatment for that condition first. This drug may cause drowsiness or dizziness, so caution is needed when driving or operating machinery. When used in conjunction with anticholinergics or specific antidepressants, antipsychotics, interactions can increase side effects, hence caution is advised. It is best not to administer this medication to pregnant women or women of childbearing potential as safety has not been established, and it is advisable for breastfeeding women to discontinue nursing while taking this medication. It is advisable not to use this medication in children as its safety has not been confirmed, and for the elderly, as liver and kidney functions may be impaired, it should be cautiously administered starting with a lower dosage. In cases of overdose, severe symptoms such as hallucinations, agitation, seizures, urinary disturbance, heart irregularities may occur; immediate medical treatment is required. This medication must be stored out of reach of children and transferring it to other containers may affect the quality of the drug, hence caution is needed.

Side effects

  • Hallucinations
  • delusions
  • paralytic ileus
  • severe constipation
  • abdominal distension
  • palpitations
  • ectopic beats
  • bradycardia
  • QT prolongation
  • ventricular tachycardia
Show 69 more
  • atrioventricular block
  • thrombocytopenia
  • renal impairment
  • urinary retention
  • Stevens-Johnson syndrome
  • fever
  • erythema
  • itching
  • conjunctival injection
  • stomatitis
  • increased intraocular pressure
  • acute glaucoma attack
  • nausea
  • headache
  • hepatic dysfunction
  • jaundice
  • myalgia
  • weakness
  • elevated CK
  • rhabdomyolysis
  • dizziness
  • headache
  • paresthesia
  • drowsiness
  • insomnia
  • tremors
  • altered consciousness
  • perceptual disturbances
  • transient forgetfulness
  • Parkinsonism
  • dyskinesia
  • hypotension
  • hypertension
  • chest pain
  • hypersensitivity
  • itching
  • rash
  • hives
  • regulatory dysfunction
  • dry eye syndrome
  • elevated AST
  • elevated ALT
  • elevated ALP
  • elevated BUN
  • elevated creatinine
  • leukopenia
  • fatigue
  • lethargy
  • swelling
  • weakness
  • taste disturbance
  • low back pain
  • hoarseness
  • sputum
  • agitation
  • heat due to decreased sweating
  • frailty
  • pharyngalgia
  • delusions
  • agitation
  • generalized seizures
  • gait disturbance
  • speech impairment
  • mydriasis
  • urinary retention
  • tachycardia
  • hypertension
  • generalized flushing
  • liver dysfunction

Not everyone experiences these, and they can vary from person to person.

Storage

This drug is sensitive to air and moisture, so it should be stored in a tightly closed container. It is recommended to maintain storage temperatures between 1 to 30 degrees Celsius to ensure the safety of the drug's effectiveness.

Appearance and packaging

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.