Medication info
Hiroxicin 250 mg (Levofloxacin Hydrate)

Hiroxicin 250 mg (Levofloxacin Hydrate)

Prescription medicationTablet경구
Ingredient · strength
Levofloxacin Hydrate›256.15mg / 1 tablet
Manufacturer / importer
(주)화이트생명과학
Appearance
Pinkish rectangular film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201402851 · Approved 2014.06.26 · Insurance code 625200380

Summary

Main use
Treatment of complicated skin and soft tissue infections, community-acquired pneumonia, and other bacterial infections
Who takes it
Adults
Adult dose
For adults, Levofloxacin is usually administered orally at a dose of 250-750 mg once daily. 1. Patients with normal kidney function (creatinine clearance exceeding 80 mL/min) - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10-14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute sinusitis: 10-14 days - Chronic bacterial prostatitis: 28 days - Complicated urinary tract infections including mild to moderate acute pyelonephritis: 250 mg every 24 hours for 10 days - Simple urinary tract infections: 3 days

Ingredients

Manufacturer
(주)화이트생명과학

Efficacy & effects

Treatment of complicated skin and soft tissue infections, community-acquired pneumonia, and other bacterial infections

  • Complicated skin and soft tissue infections
  • community-acquired pneumonia
  • acute bacterial exacerbation of chronic bronchitis
  • acute sinusitis
  • chronic bacterial prostatitis
  • acute pyelonephritis
  • complicated urinary tract infections
  • simple urinary tract infections
View approved original text

This medication is effective against various bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli, and is used to treat complicated skin and soft tissue infections, community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, acute sinusitis, chronic bacterial prostatitis, and urinary tract infections such as pyelonephritis. However, as a fluoroquinolone class drug, it carries a risk of serious adverse reactions and should be used only when no other treatment options are available for these infections. In summary, this drug effectively treats various bacterial infections and helps improve the patient's condition.

How to take

Adult dose

For adults, Levofloxacin is usually administered orally at a dose of 250-750 mg once daily. 1. Patients with normal kidney function (creatinine clearance exceeding 80 mL/min) - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10-14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute sinusitis: 10-14 days - Chronic bacterial prostatitis: 28 days - Complicated urinary tract infections including mild to moderate acute pyelonephritis: 250 mg every 24 hours for 10 days - Simple urinary tract infections: 3 days

Precautions

This drug can cause tendon-related disorders such as tendinitis and tendon rupture, so treatment should be discontinued immediately if there is pain or inflammation in the tendons. Additionally, it may induce peripheral neuropathy, central nervous system adverse effects, and exacerbation of symptoms in patients with myasthenia gravis, requiring caution. Patients with a history of severe myasthenia gravis should not use this drug, and those at risk for seizures or convulsions should use it cautiously. This medication is not to be administered to adolescents under 18 years of age or to women who are pregnant or breastfeeding. Elderly patients or those with impaired kidney function may experience an increase in drug concentration, necessitating dosage adjustment and interval changes. This medication can cause serious allergic reactions, cardiac arrhythmias, liver dysfunction, blood disorders, gastrointestinal disturbances, skin rashes, and various other side effects, and any abnormal symptoms should be reported to a healthcare provider immediately. Particularly, there is a need for caution as severe skin reactions, aortic aneurysm, aortic dissection, and valve regurgitation symptoms may occur. This drug can interact with other medications, so inform healthcare providers when using non-steroidal anti-inflammatory drugs, anticoagulants, or antihyperglycemic agents. Additionally, precautions should be taken to avoid strong sunlight or ultraviolet exposure during treatment, and care should be exercised when driving or operating machinery, as dizziness or drowsiness may occur. In case of overdose, central nervous system symptoms and cardiac abnormalities may appear, necessitating timely medical attention.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and very severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Insomnia
  • dizziness
  • headache
  • tremors
  • anxiety
  • depression
  • psychotic reactions
  • restlessness
  • confusion
  • visual and auditory disturbances
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  • taste and smell disorders
  • hallucinations
  • mania
  • sensory neuropathy
  • sensory loss
  • weakness
  • palpitations
  • QT interval prolongation
  • arrhythmia
  • elevated BUN and serum creatinine
  • nausea
  • vomiting
  • abdominal discomfort
  • diarrhea
  • loss of appetite
  • abdominal pain
  • abdominal bloating
  • indigestion
  • stomatitis
  • glossitis
  • dryness of the mouth
  • constipation
  • genital candidiasis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. It's important to keep the storage temperature between 1 degree and 30 degrees Celsius at room temperature. Proper storage will help maintain the effectiveness of the drug safely.

Appearance and packaging

Appearance

Pinkish rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.