Tuitol 400 mg (Ethambutol Hydrochloride)

Adult dose

1. Initial treatment Administer ethambutol hydrochloride orally at a dose of 15 mg/kg body weight once every 24 hours. 2. Retreatment Administer this drug at a dose of 25 mg/kg body weight once every 24 hours. After 60 days of treatment, administer 15 mg/kg body weight once every 24 hours. When administering 25 mg, have an eye examination once a month. As a rule, administer concomitantly with other antituberculosis drugs. Adjust the dose as appropriate according to age and symptoms.

This medicine should not be used in certain patients. For example, patients who have had allergic reactions to this drug or its components, or patients with optic neuritis should not take this medication. Patients with diabetes or alcohol addiction, infants and young children generally should not use this medication, but in essential cases, it must be taken very cautiously. Especially in infants and young children, it is difficult to detect visual disabilities early, so caution is necessary. Patients with decreased kidney function or those with hyperuricemia and gout should also use this medication with caution. This medication may affect vision, and symptoms such as vision deterioration, visual field constriction, and color perception abnormality may occur, so patients should frequently check their eye condition while taking it. If abnormal symptoms appear, they should stop taking the medication immediately. Neurological side effects such as leg numbness or peripheral neuropathy may rarely occur, and if symptoms such as hallucinations, anxiety, insomnia, headache, or dizziness occur, the medication should be stopped. Severe skin reactions, such as skin rashes, itching, or in severe cases, Stevens-Johnson syndrome may occur, so if there are any skin abnormalities, consult a doctor immediately. Gastrointestinal symptoms such as loss of appetite, nausea, vomiting, and stomach pain may occur, and liver function abnormalities may rarely occur, so regular liver function tests are necessary. Severe allergic reactions or symptoms such as difficulty breathing and face swelling require immediate discontinuation of the medication and emergency treatment. Symptoms of pneumonia, decreased blood cell count, and kidney function abnormalities may also rarely occur, so report any unusual symptoms to your doctor immediately. While taking this medication, regular vision checks should be conducted, especially in elderly patients or those with decreased kidney function or diabetes. Women who are pregnant or may become pregnant should carefully consider the benefits and risks before taking this medication, and those who are breastfeeding should avoid taking it if possible or discontinue breastfeeding. In the case of an overdose, symptoms such as vomiting, abdominal pain, mental confusion, and hallucinations may occur, so immediate medical attention is required. There is no specific antidote, so emergency treatment corresponding to the symptoms is necessary. Furthermore, this medication may interact with other drugs, so it should be taken with caution under medical supervision, especially when taken with rifampicin, as it may worsen visual disturbances.

• Vision loss
• central scotoma
• visual field constriction
• abnormal color perception
• paralysis of the lower limbs
• peripheral neuropathy
• hallucinations
• anxiety
• insomnia
• headache

This medication must be stored in a tightly sealed container to protect it from air and light, and it should be safely stored at room temperature between 1 to 30 degrees Celsius. This way of storage helps maintain the medication's effectiveness.

Appearance

Yellow round film-coated tablet

Package unit

60 tablets (10 tablets/PTP x 6)