Itrix Tablet (Itraconazole)

Adult dose

It is preferable to take this medication immediately after a meal. Vulvovaginal candidiasis: Administer 200mg of itraconazole per dose twice daily (morning and evening) for 1 day, or 200mg once daily for 3 days. Tinea versicolor: Administer 200mg once daily for 7 days. Tinea corporis, tinea cruris: Administer 100mg once daily for 15 days. Tinea manuum (interdigital), tinea pedis (interdigital): Administer 100mg once daily for 15 days. Tinea manuum (palmar), tinea pedis (plantar): Administer 100mg once daily for 30 days or 200mg per dose twice daily for 7 days. Oropharyngeal candidiasis: Administer 100mg once daily for 15 days. Fungal keratitis: Administer 200mg once daily for 21 days. Onychomycosis pulse therapy: Administer 200mg per dose twice daily for 1 week, followed by a 3-week drug-free period; this constitutes 1 cycle. Administer up to 2 cycles if only the fingernails are infected, and up to 3 cycles if the toenails are infected. Toenails (with or without accompanying fingernail infection): 1 week of treatment, 2 weeks off treatment, 3 weeks of treatment, 4 weeks off treatment, 5 weeks of treatment Fingernails: 1 week of treatment, 2 weeks off treatment, 3 weeks of treatment Onychomycosis continuous therapy: Administer 200mg once daily for 3 months. Aspergillosis: 200mg once daily for 2~5 months. For invasive or disseminated disease, increase the dose to 200mg per dose twice daily. Candidiasis: 100~200mg once daily for 3 weeks~7 months Cryptococcal meningitis: 200mg twice daily for 2 months~1 year Maintenance treatment for cryptococcal meningitis: 200mg once daily Paracoccidioidomycosis: 100mg once daily for 6 months For patients with impaired immune function, such as those with neutropenia or AIDS or those who have undergone organ transplantation, increase the dose twofold if necessary.

It is extremely important not to use this medication in patients with impaired cardiac function, particularly in those with congestive heart failure or a history of heart failure. If symptoms of heart failure occur while using this medication, it should be discontinued immediately. This medication should never be used in case of hypersensitivity. Moreover, it is crucial not to combine this drug with certain medications as it may lead to severe side effects. For instance, the risk may be higher when used in conjunction with some analgesics, antiarrhythmics, anticoagulants, and antipsychotic medications. Women who are pregnant or may become pregnant, as well as nursing mothers, should not use this medication and should apply effective contraceptive measures after use. Patients with impaired liver function or a history of hepatotoxicity should be given this medication with caution, and regular liver function tests should be conducted to detect any abnormalities early. Patients with reduced kidney function also require cautions, and dose adjustment may be necessary. This medication can interact with various drugs, so patients currently taking other medications should consult their healthcare professionals. Especially when taken with acid-reducing drugs, absorption may decrease; therefore, it is recommended to take it with acidic beverages. Rarely, this medication may cause serious adverse reactions such as severe liver damage, heart problems, allergic reactions, neurological abnormalities, and hearing loss. If any unusual symptoms occur, patients should consult a physician immediately. In children and the elderly, this medication should be administered with caution and should only be used if the benefits of treatment outweigh the risks. In cases of overdose, there is no specific antidote, so patients should immediately receive appropriate treatment in a medical facility, and this drug is not removed by hemodialysis. Finally, this medication should be stored out of reach of children and kept in its original container to prevent misuse or deterioration in quality.

Decreased myocardial contractility, headache, nausea, abdominal pain, rhinitis, sinusitis, upper respiratory infection, leukopenia, hypersensitivity, dysgeusia, decreased perception, perceptual abnormalities, tinnitus, constipation, diarrhea, dyspepsia, vomiting, liver dysfunction, hyperbilirubinemia, pruritus, rash, urticaria, pollakiuria, erectile dysfunction, menstrual disorders, edema, granulocytopenia, thrombocytopenia, anaphylactic reaction, hyperglycemia, hyperkalemia, hypokalemia, hypomagnesemia, confusional state, peripheral neuropathy, dizziness, drowsiness, tremors, heart failure, left ventricular failure, tachycardia, hypertension, hypotension, pulmonary edema, speech impairment, cough, gastrointestinal disorders, liver failure, hepatitis, jaundice, erythematous rash, hyperhidrosis, myalgia, arthralgia, renal impairment, incontinence, generalized edema, facial edema, chest pain, fever, pain, fatigue, chills, increased alanine aminotransferase, increased aspartate aminotransferase, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased serum urea, increased gamma-glutamyl transferase, elevated liver enzymes, abnormal urinalysis, leukocytosis, eosinophilia, anemia, vascular edema, serum sickness, vasogenic edema, anaphylaxis, anaphylactic shock, allergic reaction, diplopia, visual impairment, hearing loss, ventricular extrasystole, atrioventricular block, palpitations, increased bowel motility, belching, glossitis, stomatitis, abdominal and lower back pain, pancreatitis, elevated serum total protein, increased total bilirubin, increased LAP, decreased appetite, lethargy, brown urine, elevated liver enzyme levels, mucous membrane pemphigoid, Stevens-Johnson syndrome, toxic epidermal necrolysis, Lyell's syndrome, erythema multiforme, hair loss, photosensitivity reaction, exfoliative dermatitis, leukocytoclastic vasculitis, acute generalized exanthematous pustulosis, increased BUN, positive urine protein test, positive urine glucose test, decreased libido, drowsiness, shoulder stiffness, insomnia, chest pain, increased serum triglyceride levels, warmth, increased serum uric acid levels, increased serum potassium levels, serum sickness, vasogenic edema, anaphylaxis reaction, hypertriglyceridemia, tremors, visual impairment, transient hearing loss, permanent hearing loss, congestive heart failure, dyspnea, significant hepatotoxicity, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, increased serum creatine phosphokinase

This medication should be stored in a tightly sealed container to prevent exposure to air and is best kept at room temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the efficacy of the drug and prevents it from deteriorating.

Appearance

White egg-shaped film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle