Koryo Cephalexin Capsule (Cephalexin Hydrate)

Adult dose

As Cephalexin Hydrate, take 250 mg (potency) orally every 8 hours. For severe infections and those with low susceptibility, the dosage may be doubled. For acute gonococcal urethritis, administer this medication 3 g combined with 1 g probenecid as a single dose.

Child dose

Administer 20 mg (potency) per kg of body weight divided every 8 hours. For severe infections, otitis media, and infections with low susceptibility, 40 mg (potency) per kg of body weight may be administered, with a maximum dosage of 1

This medication works by binding to certain proteins to inhibit bacterial cell wall synthesis, thereby killing bacteria. Before using this medication, individuals who have previously experienced severe allergic reactions or shock from this medication or cephalosporin antibiotics should not use it. Caution is also required for those with allergies to penicillin antibiotics or those with a tendency to frequently exhibit allergic symptoms such as asthma or skin rashes. Patients with severely impaired renal function, those unable to take orally, elderly individuals, or those with compromised overall health should be monitored closely due to the risk of bleeding associated with vitamin K deficiency. Patients with a history of gastrointestinal disorders, particularly colitis, should also take caution when using this medication. Rarely, this medication may cause severe allergic reactions, skin rashes, blood abnormalities, liver or kidney function abnormalities, digestive issues, respiratory issues, central nervous system abnormalities, and if any abnormal symptoms occur, medical personnel should be informed immediately. In particular, if severe diarrhea or abdominal pain occurs, it may indicate serious colitis such as pseudomembranous colitis, so use should be stopped immediately, and a doctor's consultation is necessary. When administering this medication, sensitivity tests should be conducted to prevent antibiotic resistance, and it is advisable to use it only for the minimum necessary duration. Additionally, concurrent use with other medications may cause interactions, particularly with medications that may affect the kidneys, anticoagulants, or oral contraceptives, which must be approached with caution. Pregnant or breastfeeding women should only use this medication when the benefit outweighs the risk, as its safety has not been fully established, and caution is required while breastfeeding. This medication should not be used in newborns under one month of age, as its safety and efficacy have not been established. Elderly patients may experience side effects more easily due to decreased bodily function, so dose adjustments and monitoring are necessary. Finally, it is important to inform medical personnel of this medication when undergoing urine tests, as it may affect the results.

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, shock, anaphylactic symptoms (generalized flushing, swelling, difficulty breathing, angioedema, sensory disturbances, syncope, hypertension, vasodilation), Stevens-Johnson syndrome, toxic epidermal necrolysis, agranulocytosis, granulocytopenia, pancytopenia, anemia, thrombocytopenia, aplastic anemia, hemolytic anemia, liver abnormalities (transient hepatitis, jaundice, elevated AST, ALT, ALP), reversible interstitial nephritis

Mild side effects

• Rash
• itching
• fever
• lymphadenopathy
• arthralgia
• serum sickness-like reaction
• nausea
• vomiting
• diarrhea
• abdominal pain

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius. This helps to preserve the drug's effectiveness and ensure safe usage.

Appearance

A hard capsule with an upper purple and lower white appearance filled with pale yellow powder.

Package unit

30 capsules/bottle, 300 capsules/bottle