Selond Tablet (Methylprednisolone)

Adult use

The initial dose may vary from 4mg to 48mg of methylprednisolone per day, depending on the symptoms of the specific disease. In general, a low dose is sufficient for conditions that are not severe, although a high initial dose may be required in certain patients. The initial dose should be maintained or adjusted until a satisfactory response is obtained. If there is no satisfactory clinical result after a reasonable period, discontinue treatment and switch to another appropriate therapy. The dose must be determined individually according to the disease being treated and the patient's response. After an adequate response is achieved, determine an appropriate maintenance dose by reducing the initial dose at suitable intervals until the lowest dose that maintains an adequate clinical response is reached. Continuous monitoring of the dose is required. Situations that may require dose adjustment include improvement or worsening of the disease, the individual patient's response to the medicine, and the effect on the patient of exposure to stressful circumstances that are not directly related to the symptoms of the disease being treated. In the latter case, it may be necessary to increase the dose for a period sufficient to achieve a satisfactory clinical condition. After long-term treatment, gradual dose reduction is recommended when discontinuing the medicine. Multiple sclerosis For treatment of acute exacerbations of multiple sclerosis, administration of prednisolone 200mg daily for 1 week, followed by prednisolone 80mg every other day for 1 month, is effective (4mg of methylprednisolone is equivalent to 5mg of prednisolone). ADT (Alternate Day Therapy) Alternate-day therapy is a regimen in which twice the daily dose is administered on one morning every other day.

This drug should not be administered to certain patients. For instance, those with an allergy to this drug or its ingredients, infections without appropriate antibiotics, systemic fungal infections, patients with herpes simplex, herpes zoster, chickenpox, or those receiving live or attenuated vaccines may face risks. Additionally, this drug contains lactose and should not be used in patients with lactose intolerance or related genetic issues. There are also patients for whom this drug should be used cautiously. Patients with glaucoma, tuberculosis, cataracts, electrolyte imbalances, hypertension, thrombosis, recent surgery, heart disease, peptic ulcers, psychiatric disorders, osteoporosis, diabetes, renal failure, hypothyroidism, fatty liver, myasthenia gravis, elderly patients, epilepsy, and ulcerative colitis should be particularly careful when using this drug. Since various side effects may occur when taking this drug, careful monitoring is required. Possible side effects may include swelling, electrolyte imbalances, muscle weakness, osteoporosis, gastrointestinal issues, skin changes, mental and neurological symptoms, endocrine issues, visual disturbances, and immune system problems. Long-term use of this drug can lead to adrenal insufficiency, so it should not be abruptly discontinued, and the dosage should be gradually reduced. In stress situations such as infections, surgeries, or trauma, the dosage may need to be temporarily increased. This drug may interact with other medications, so it is essential to consult a doctor or pharmacist if combining it with other drugs. Special caution is needed when used alongside drugs that affect heart rhythm, anticoagulants, hypoglycemic agents, diuretics, antibiotics, and antifungals. Women who are pregnant or may become pregnant should only use this drug when the benefits of treatment outweigh the risks to the fetus, and breastfeeding should be avoided while taking this drug. This drug may affect children's growth, so it should be used carefully at the minimal effective dose, and elderly patients should be monitored closely for potential side effects. Extra care should be taken to avoid infections from chickenpox or measles while taking this drug, and if an infection is suspected or occurs, medical examination and appropriate treatment should be sought immediately.

Edema, sodium retention, potassium loss, fluid retention, hypokalemic alkalosis, congestive heart failure, hypertension, myasthenia, aseptic necrosis of the femoral and humeral epiphyses, steroid myopathy, loss of muscle mass, pathological fracture of the iliac bone, osteoporosis, vertebral compression fracture, arthralgia, tendon rupture, increased ALT, increased AST, increased ALP, nausea, thirst, vomiting, gastric pain, loss of appetite, increased appetite, peptic ulcer, abdominal distention, pancreatitis, ulcerative esophagitis, diarrhea, delayed wound healing, facial erythema, thin and fragile skin, abnormal sweating, petechiae, purpura, suppression phenomena of skin reactions, purpura, acne, hirsutism, hair loss, pigmentation, papill edema, increased intracranial pressure, convulsions, dizziness, headache, insomnia, euphoria, depression, Cushing's syndrome, menstrual irregularities, growth suppression in children, symptoms of latent diabetes, secondary adrenal insufficiency, pituitary unresponsiveness, decreased glucose tolerance, increased need for insulin or oral hypoglycemic agents, suppression of adrenal corticotropic hormone secretion, increased intraocular pressure, glaucoma, posterior subcapsular cataract, secondary eye infections, retinal disorders, exophthalmos, negative nitrogen balance, immune system disorders, allergic reactions, shock, urticaria, anaphylactic reactions, hypersensitivity reactions

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. The storage temperature should be maintained between 1 degree and 30 degrees Celsius.

Appearance

White oval tablet

Package unit

30 tablets/bottle, 500 tablets/bottle