Fronclar Capsule (Cefaclor Hydrate)

Adult dose

As cefaclor, orally administer 250mg (potency) every 8 hours. In cases of severe infections (such as pneumonia) and infections with low susceptibility, the dosage can be doubled. For acute gonococcal urethritis, administer this medicine 3g along with 1g of probenecid in a single dose.

Child dose

Administer 20mg (potency) per kg of body weight divided every 8 hours. In cases of severe infections, otitis media, and infections with low susceptibility, 40mg (potency) per kg of body weight may be administered, with a maximum dosage of

This medicine should not be used in patients who have previously experienced severe allergic reactions or shock due to this medicine or cephalosporin antibiotics. Additionally, since it contains lactose, it should not be administered to patients with genetic disorders affecting lactose digestion. Care should be taken when using this medicine in patients allergic to penicillin or those who are prone to allergies like asthma, rashes, and hives. Patients with severely impaired kidney function, those who find it difficult to take orally, elderly patients, and patients in poor general condition should also be monitored closely while using this medicine. Patients with a history of gastrointestinal disease, especially colitis, should receive careful administration. This medicine can rarely cause severe allergic reactions, skin diseases, hematological abnormalities, liver and kidney dysfunction, gastrointestinal issues, respiratory problems, and central nervous system symptoms; if any symptoms appear, consult a doctor immediately. Additionally, long-term or excessive use of this medicine may lead to bleeding risks due to vitamin K deficiency, thus requiring careful monitoring. When using this medicine, it is recommended to administer it only for the minimum necessary period to prevent the emergence of resistant bacteria. Interactions may occur when used in combination with probenecid, certain antacids, or drugs affecting the kidneys, so it is important to inform your doctor or pharmacist. When taken with oral contraceptives, the contraceptive effect may decrease; hence, it is advisable to use alternative contraceptive methods. Women who are pregnant or breastfeeding should use this medicine cautiously only when absolutely necessary, as its safety has not been fully established. When administering to children or elderly patients, body functions and conditions should be closely monitored, and dosage and administration intervals should be adjusted accordingly. This medicine may affect the results of some clinical tests, so it is important to inform the examiner about its use during testing. In case of overdose, symptoms such as nausea, vomiting, abdominal discomfort, and diarrhea may occur, and immediate medical attention should be sought for proper treatment.

Serious side effects

• Hives
• edema
• shortness of breath
• shock
• anaphylactic symptoms
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• jaundice
• sudden and severe headaches
• seizures

Mild side effects

• Generalized flushing
• angioedema
• sensory disturbances
• fainting
• hypertension
• vasodilation
• rash
• erythema
• itching
• fever

This medicine is sensitive to light and should be stored in a container that can block light. Additionally, it should be stored at room temperature between 1 and 30 degrees Celsius. Proper storage in this manner helps maintain the effectiveness of the medicine.

Appearance

A hard capsule with an opaque upper purple part and an opaque white lower part filled with pale yellow powder

Package unit

30 capsules/bottle, 300 capsules/bottle