Pheramine (Chlorpheniramine maleate)

Key information summary

Efficacy & effects

This medicine is used for pruritic skin disorders such as allergic rhinitis, urticaria, eczema, and dermatitis.

Dosage

As chlorpheniramine maleate, administer 5-10mg subcutaneously, intramuscularly, or intravenously once or twice a day. Adjust the dosage according to age and symptoms.

Precautions

This medication is administered by injection, and care should be taken when opening the container as glass fragments may be present. Special caution is required when used in children or the elderly. This medication contains benzyl alcohol, which can cause life-threatening respiratory problems in premature infants or newborns, and should not be administered to them. Patients with allergies to this medication, glaucoma, benign prostatic hyperplasia, premature infants, newborns, or those taking certain antidepressants (MAO inhibitors) should not use this medication. Patients with high intraocular pressure, hyperthyroidism, gastrointestinal obstruction, cardiovascular diseases, epilepsy, or asthma or bronchial diseases should use this medication cautiously. During administration, symptoms of shock, respiratory distress, and hypotension may occur, so the patient's condition should be monitored closely, and if abnormal symptoms appear, administration should be stopped immediately and proper treatment should be sought. Additionally, seizures or confusion may occur, so careful monitoring is required, and the dosage may need to be reduced or temporarily stopped if necessary. Blood-related side effects such as aplastic anemia or agranulocytosis may occur, necessitating regular blood tests. Various side effects can occur including rash, urticaria, muscle spasms, drowsiness, headache, dizziness, digestive disorders, urinary difficulties, heart irregularities, and bronchial issues, so if any abnormal symptoms arise, the patient should consult healthcare professionals. This medication may cause drowsiness; therefore, it is advised to avoid driving or operating dangerous machinery while taking it. When taken with alcohol or central nervous system depressants, drowsiness may be intensified, so caution is needed, and interaction with other medications should be discussed with a doctor or pharmacist. Women who are pregnant or may become pregnant should use this medication cautiously only if the benefit of treatment is judged to outweigh the risks, as its safety has not been established. Women who are breastfeeding should be cautious as this medication can be transferred through breast milk and may inhibit milk secretion; it should only be administered when necessary. In cases of overdose in children or infants, hallucinations, agitation, seizures, and potentially fatal outcomes may occur, so special care is needed. Elderly patients may have reduced physical function, so their condition should be observed closely and administered cautiously. In cases of overdose, serious central nervous system disturbances, cardiac, and respiratory issues may arise; immediate treatment should be sought at a medical institution.

Side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, shock, cyanosis, hypotension, seizures, confusion, jaundice.

Alternatives / Same-ingredient medications

• Pheniramine Injection (Chlorpheniramine Maleate)

  Same ingredient
• Pheniramine Tablets (Chlorpheniramine Maleate)

  Same ingredient
• Huons Chlorpheniramine Maleate Injection Solution

  Same ingredient

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