Tianeptine Tablets (Sodium Tianeptine)

Adult dose

Adults: Administer 12.5 mg of tianeptine sodium orally 3 times daily before meals. In older patients aged 70 years or older or patients with renal impairment, limit administration to twice daily. The dose may be adjusted according to symptoms. Abrupt discontinuation of treatment should be avoided. To reduce the risk of withdrawal reactions, the dose should be tapered gradually over 7 ~ 14 days. (See “General Precautions” under Precautions for Use.)

This medication is used for the treatment of depression and may increase the risk of suicidal thoughts or self-harm, so patients should be closely monitored for the first few weeks of treatment. Particularly, patients with a history of suicidal attempts or thoughts require extra caution. This medication should not be used by children under 15 years of age, patients with certain rare genetic diseases, or those taking specific medications (MAO inhibitors). When taking this medication, various side effects such as decreased appetite, nightmares, insomnia, drowsiness, dizziness, palpitations, gastrointestinal discomfort, and skin rashes may occur; any unusual symptoms should be discussed with a doctor. Patients scheduled for surgery should inform their anesthesiologist about taking this medication, and may need to stop the medication 1 to 2 days prior to the procedure if necessary. Concurrent use of this medication and alcohol may increase the risk of side effects and should be avoided. Abrupt discontinuation of the medication may result in withdrawal symptoms such as anxiety, muscle pain, and insomnia, so the dosage should be gradually reduced under a doctor's guidance. Caution is needed as drowsiness may occur while driving or operating machinery. For patients with decreased kidney function or elderly patients, the frequency of dosing should be limited as drug concentrations may increase. In case of overdose, symptoms such as drowsiness and coma may occur; immediate medical treatment should be sought. Keep out of reach of children and do not transfer to another container for safety.

• Loss of appetite
• hyponatremia
• nightmares
• drug abuse and dependence
• suicidal ideation
• suicidal behavior
• confusion
• hallucinations
• insomnia
• drowsiness

This medication should be stored in a tightly closed container to protect it from air and moisture. It is advisable to maintain storage temperatures between 1 and 30 degrees Celsius at room temperature.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle