Medication info

Codesmo Desmopressin 0.2mg (Desmopressin Acetate)

Prescription medicationOralExpired
Ingredient · strength
Desmopressin Acetate›0.2mg / 1 packet
Manufacturer / importer
Kolin Pharmaceutical Co., Ltd.
Appearance
White or pale yellow powder
Packaging
Company packaging unit
Approval status
Expired

MFDS item code 201400879 · Approved 2014.02.26

This product's status changed to Expired on 2024.02.26. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of primary nocturnal enuresis (age 5 years and older) and nocturia associated with nocturnal polyuria (adults)
Who takes it
Adults · Children
Adult dose
Treatment of nocturia associated with nocturnal polyuria (adults only) Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose adjustment.
Child dose
Primary nocturnal enuresis (5 years and older) Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased up to 0.4mg. Whether to continue treatment should be determined after 3 months of administration, following a treatment-free period of at least 1 week.

Ingredients

Manufacturer
Kolin Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of primary nocturnal enuresis (age 5 years and older) and nocturia associated with nocturnal polyuria (adults)

  • Primary enuresis
  • nocturia symptoms
View approved original text

This medication is used to treat nocturia symptoms associated with primary enuresis in children aged 5 years and older and adults. It helps alleviate the symptoms of frequent urination at night and improve the quality of sleep. It can effectively manage the patient's nocturia issues, reducing discomfort in daily life.

How to take

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose adjustment.

Child dose

Primary nocturnal enuresis (5 years and older) Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased up to 0.4mg. Whether to continue treatment should be determined after 3 months of administration, following a treatment-free period of at least 1 week.

Precautions

This medication can cause hyponatremia and water intoxication, so particularly elderly patients or those with certain medical conditions should limit fluid intake to the degree needed to satisfy thirst. Patients with a history of allergic reactions to this medication, heart failure, those taking diuretics, and patients with impaired kidney function should not use this medication. Individuals with high blood pressure, chronic kidney disease, women of childbearing potential, children, and the elderly should take special care when using this medication, and those with fluid and electrolyte imbalances must have their conditions thoroughly evaluated before treatment. During the use of this medication, symptoms such as headache, nausea, weight gain, and seizures may occur, so any abnormal symptoms should be reported to a healthcare professional immediately. Fluid intake should be restricted from one hour before administration until at least 8 hours after administration, and in cases of poor kidney function, it should be restricted even more strictly. This medication can interact with other drugs, so caution is needed when taking tricyclic antidepressants, diuretics, non-steroidal anti-inflammatory drugs, etc. Pregnant or breastfeeding women should make careful decisions considering the effects on the fetus or newborn, and if breastfeeding, it is advisable to discontinue breastfeeding. In case of overdose, symptoms of hyponatremia and fluid retention, such as headache, seizures, and loss of consciousness, may occur, so a healthcare professional should be notified immediately, and treatment such as administering diuretics may be necessary.

Side effects

  • coma
  • convulsions
  • weight gain
  • hyponatremia
  • emotional disorders
  • headache
  • abdominal pain
  • nausea
  • allergic skin reactions
  • dizziness
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  • peripheral edema
  • polyuria
  • thirst
  • vomiting
  • weight increase
  • cold sensation
  • loss of consciousness

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. The storage temperature should be maintained between 1 to 30 degrees Celsius at room temperature. This will help maintain the medication's efficacy for a longer duration.

Appearance and packaging

Appearance

White or pale yellow powder

Package unit

Company packaging unit

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.