Crestba Tablet 20mg (Rosuvastatin Calcium)

Adult dose

For adult patients with primary hypercholesterolemia and others, this medication can be taken once daily at any time of the day, regardless of meals. The initial dose is 5 milligrams once daily, and the maintenance dose is often adjusted to 10 milligrams once daily for most patients. After an interval of 4 weeks or more, the maintenance dose should be adjusted based on LDL-cholesterol levels, treatment goals, and patient response, potentially escalating to a maximum of 20 milligrams daily.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dose is administered once daily at a range of 5 milligrams to 20 milligrams. The dosing should be adjusted based on the treatment goals for each individual patient.

This medication should not be administered to certain patients, such as those with an allergy to this drug, severe liver disease, or muscle disorders, as well as those taking certain medications, severely impaired renal function patients, and women who are pregnant or breastfeeding. It is important to regularly monitor liver function and muscle condition before and during treatment, especially for patients with a history of liver disease or who consume alcohol heavily. If symptoms like muscle pain or weakness occur, patients should notify healthcare professionals immediately, and treatment may need to be discontinued in severe cases. This medication contains lactose, so patients with lactose intolerance should avoid taking it. Additionally, this drug may interact with other medications, so patients should inform their healthcare provider about any other medications they are taking, especially with certain antiviral drugs, immunosuppressants, and fibrate medications. Women with childbearing potential should use appropriate contraceptive methods, and those who are pregnant or breastfeeding should avoid taking it. In cases of overdose, there is no specific antidote, and symptomatic treatment should be initiated while monitoring liver function and muscle enzyme levels. This drug may cause side effects such as dizziness, so caution is advised when driving or operating machinery. Finally, rare but serious side effects such as interstitial lung disease or severe skin reactions may occur with long-term use, so patients should consult healthcare professionals immediately if any unusual symptoms appear.

Serious side effects

Allergic reactions including hives and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), rhabdomyolysis, myopathy, severe muscle weakness, ocular myasthenia, jaundice, hepatitis, severe liver damage, fatal and non-fatal liver failure, severe edema, acute kidney failure, oliguria, severe allergic reactions, severe skin reactions, dyspnea, respiratory issues, severe neurological effects

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• muscle pain
• weakness
• cough

This medication may be sensitive to air and moisture, so it must be stored in a tightly closed container. It is recommended to maintain the storage temperature between 1 degree to 30 degrees Celsius. This will help preserve the medication's effectiveness and safety over time.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle