Amiclan Duo Tablet 500 mg (Amoxicillin Hydrate, Clavulanate Potassium) (7:1)

Adult dose

For severe infections and respiratory infections, take 2 tablets orally, twice a day every 12 hours.

This drug should not be used in patients who have had hypersensitivity reactions to specific components or beta-lactam antibiotics. Caution is especially needed in patients with viral infections such as infectious mononucleosis or lymphocytic leukemia, as there is an increased risk of rash. Patients with liver dysfunction or genetic metabolic disorders such as lactose intolerance should not take this drug. Additionally, it should be administered cautiously to patients with liver impairment or severe renal impairment, as drug concentration may increase. Gastrointestinal symptoms such as diarrhea, abdominal pain, and vomiting may occur during treatment with this drug, and if serious gastrointestinal symptoms such as pseudomembranous colitis arise, the medication should be discontinued immediately and a doctor's care sought. Various side effects can occur, including liver dysfunction, skin rash, hypersensitivity, blood disorders, and nervous system abnormalities, so any unusual symptoms should be reported to healthcare professionals immediately. Severe allergic reactions may occur in patients with allergic predispositions or those who have had hypersensitivity reactions to penicillin drugs, so a medical history must be confirmed before administration. For long-term use, liver and kidney functions, as well as blood conditions, should be regularly evaluated, and care should be taken not to exceed the necessary duration of use. Women who are pregnant or breastfeeding should carefully consider the effects of this drug on the fetus or infant, and it is particularly advisable to avoid administration during the first trimester of pregnancy. This drug may interact with other medications, so if you are taking any other drugs, be sure to consult your doctor or pharmacist. For example, caution is needed when taken in conjunction with anticoagulants, certain antibiotics, and anti-inflammatory drugs. In case of overdose, gastrointestinal symptoms, kidney dysfunction, or central nervous system abnormalities may occur, so immediate medical contact should be made for appropriate treatment. When storing, it is best to avoid direct sunlight and keep it in a cool, dry place below 25 degrees Celsius, out of reach of children.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions (anaphylaxis, anaphylactic shock), severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis), asthma attacks, respiratory abnormalities associated with cough and fever, jaundice of the skin or eyes

Mild side effects

Diarrhea, pseudomembranous colitis, indigestion, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, bloating, constipation, colonic pain, hyperacidity, loose stools, dry mouth, candidiasis, antibiotic-associated colitis, itching, erythema multiforme, dermatitis, serum sickness rash, arthralgia, edema, lymphadenopathy, blood system abnormalities (leukopenia, thrombocytopenia, hemolytic anemia, anemia, thrombocytosis, bone marrow suppression, etc.)

This drug should be stored in a sealed container to prevent humidity and should be kept in a cool, dry place between 1 and 25 degrees Celsius. Avoiding moisture and high temperatures will help maintain the drug's effectiveness over time.

Appearance

White oval film-coated tablets

Package unit

80 tablets/box (8 tablets/PTP×10)