Nazeron Injection 0.3 mg (Vial) (Ramosetron Hydrochloride)

Adult administration

Administer 0.3 mg of Ramosetron Hydrochloride intravenously once a day. If the effect is insufficient, the same dose may be administered again. However, do not exceed 0.6 mg in a single day. Adjust the dosage appropriately based on symptoms.

This drug should not be used in patients who show allergic reactions to this drug or its other components. Care should be taken when administering this drug to patients currently taking other serotonergic drugs, such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs). Serious allergic reactions, such as shock or anaphylaxis, may occur rarely while this drug is being used; if any abnormal symptoms arise, administration should be stopped immediately and appropriate treatment should be obtained. Additionally, cases of seizures similar to epilepsy have been reported, so caution is required for patients with a history of seizures. Some patients may experience side effects such as headaches, diarrhea, abnormal liver function, itching, and rashes, so if any abnormal symptoms persist or worsen, a doctor should be consulted. This drug is primarily metabolized in the liver, so patients with liver dysfunction or those using certain other medications may have elevated blood concentrations and should be cautious. Women who are pregnant or may become pregnant should only receive this drug if the benefits of treatment outweigh the risks, as its safety has not been established. Breastfeeding women are advised to discontinue breastfeeding, as this drug may be excreted in breast milk. Safety in children has not been sufficiently established, so caution is warranted when using it, and elderly patients may have diminished physiological functions, so their condition should be carefully monitored during administration. This drug may cause problems if mixed with certain injection solutions, so care should be taken during preparation, and it should not be mixed with recommended incompatible drugs. Finally, animal studies have reported results indicating potential effects on fetal growth, so caution is advised when used during pregnancy.

Serious side effects

Shock, anaphylaxis-like symptoms (chest discomfort, difficulty breathing, asthma), seizures resembling epilepsy

Mild side effects

Headache, heaviness in the head, rash, itching, redness, diarrhea, constipation, increased BUN, elevated serum creatinine, abnormal liver function (increased AST, increased ALT, increased r-GTP, increased bilirubin), feeling of warmth, yawning, warmth in the head, tingling in the tongue, insomnia, rash

This drug is sensitive to light and should be stored in a tightly closed container that protects it from light. Additionally, the drug should be kept away from excessively hot or cold places and maintained at a temperature between 1°C and 30°C to preserve its effectiveness.

Appearance

A clear colorless liquid in a brown vial injection

Package unit

For domestic use - 1 vial - 2 mL/vial, For domestic use - 10 vials - 2 mL/vial, For domestic use - 10 vials - 10 vials/box