Fabirazole 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: Typically, administer 10 mg orally once daily. Depending on symptoms, 20 mg may be administered orally once daily. Treatment duration is up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg once daily for 4 to 8 weeks. If symptoms persist after 8 weeks, an additional course of 10 mg or 20 mg for another 8 weeks may be required.

This medication should not be administered to patients with specific allergic reactions. For example, individuals who are hypersensitive to this drug, its components, or the benzimidazole class should not take it. Additionally, people who are allergic to penicillin or macrolide antibiotics should use this medication cautiously, especially when undergoing combination therapy aimed at eradicating Helicobacter pylori, and should consult a physician. This medication may interact with certain specific drugs, so it is essential to inform your physician about any medications you are currently taking. For example, do not use this medication if you are taking terfenadine, cisapride, pimodipine, astemizole, atazanavir, rilpivirine, and others. Women who are pregnant or breastfeeding should not take this medication, as it can affect the fetus or newborn. Patients with poor liver function or elderly individuals should exercise more caution when using this medication, and those with a history of drug allergies need to be careful. The drug contains a dye called yellow #4 (tartrazine), so caution is necessary for those allergic to this substance. During use, allergic symptoms such as skin rash, hives, and itching may occur; if such symptoms arise, discontinue use immediately and consult a physician. Regular blood tests and liver function tests are required; if abnormalities are found, discontinue the medication and receive appropriate treatment. Patients with cardiovascular issues, gastrointestinal symptoms, neurological symptoms, or respiratory symptoms may experience severe symptoms, and consultation with a physician is essential if this occurs. Long-term use of this medication may increase the risk of fractures related to osteoporosis, so bone density management is necessary during prolonged administration. Also, this medication suppresses gastric acid secretion and may increase the risk of certain bacterial infections; if diarrhea or infection symptoms persist during use, immediately inform healthcare professionals. Caution is necessary as drowsiness may occur during driving or operating machinery. There is no specific antidote for overdose, so treatment should be provided according to symptoms. Do not chew or crush the tablet; swallow it whole. When storing, keep it in a tightly closed container to prevent air or moisture ingress, and do not transfer it to another container.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, liver abnormalities (jaundice), acute interstitial nephritis, fulminant hepatitis, liver dysfunction, jaundice, sudden death, coma, anaphylaxis, angioedema, hypotension, shock, severe allergic reactions, severe skin adverse effects (toxic epidermal necrolysis (Lyell syndrome), mucous membrane syndrome (Stevens-Johnson syndrome), erythema multiforme), respiratory issues (asthma, pulmonary embolism, interstitial pneumonia), serious neurological symptoms.

Mild side effects

Rash, itching, blood system abnormalities (decreased red blood cells, decreased white blood cells, increased white blood cells, increased eosinophils, increased neutrophils, decreased lymphocytes, anemia, purpura, lymphadenopathy, hypochromic anemia, pancytopenia, agranulocytosis, decreased platelets, hemolytic anemia), elevated levels of ALT, AST, ALP, γ-GTP, LDH, total bilirubin, hypertension, myocardial infarction, ECG abnormalities, migraine, syncope, angina, heart block, palpitations, bradycardia, and others.

This medication should be stored in a tightly closed container to prevent air or moisture ingress. It is advisable to keep the storage temperature between 1 and 30 degrees Celsius, as this helps to maintain the drug's efficacy and safety.

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/AluAlu pack x 2)