CreaZinc 10mg (Rosuvastatin Calcium)

Adult dose

For adults with primary hypercholesterolemia, this medication can be taken at any time of day with or without food. The initial dose is 5 mg once daily, and it can be adjusted to maintain a dose of 10 mg once daily as needed. Maintenance doses should be adjusted based on LDL cholesterol levels and patient response at intervals of at least 4 weeks, up to a maximum of 20 mg once daily.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years), the dosage is administered once daily in the range of 5 mg to 20 mg. The dosage is adjusted individually according to therapeutic objectives.

This medication should not be used in certain patients. For example, it should not be administered to patients who are allergic to any of its components, patients with severely impaired liver function, patients with muscle diseases, or patients with severe renal impairment, as well as women who are pregnant or breastfeeding. Furthermore, patients who consume excessive alcohol or have a history of liver disease should frequently undergo liver function tests before taking this medication. They should inform healthcare providers immediately if they experience any symptoms of muscle pain or weakness, and in severe cases, they may need to discontinue the medication. This medication may increase the risk of muscle damage when taken with certain drugs, so patients must consult with healthcare providers if they are taking other medications. Caution is especially needed when combined with fibrate drugs. Women of childbearing potential should use appropriate contraception, and this medication should not be taken during pregnancy. It is also advisable to avoid this medication while breastfeeding. In case of overdose, there is no specific antidote, and treatment should be based on symptoms, monitoring liver function and muscle enzyme levels. This medication may rarely cause side effects such as headache, dizziness, muscle pain, dyspepsia, skin rash, so if any unusual symptoms persist or worsen, patients should consult healthcare providers. Caution is required as dizziness may occur when driving or operating machinery. Lastly, this medication may have a higher plasma concentration in Asians, so dosage adjustments may be necessary.

Serious side effects

Hypersensitivity reactions including urticaria and angioedema, severe swelling (edema), chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe liver damage, acute renal failure, oliguria, severe muscle weakness, ocular muscle weakness, immune-mediated necrotizing myopathy, rhabdomyolysis, severe skin adverse reactions, dyspnea, asthma attacks, headache, confusion

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication should be stored in a tightly closed container to prevent air or moisture from entering and should be kept at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness for a longer period.

Appearance

Pink round film-coated tablets

Package unit

28 tablets/Alu-Alu PTP (7 tablets/Alu-Alu PTP*4)