Genewon Olmesartan Tablet 40mg (Olmesartan Medoxomil)

Adult dose

The recommended initial dose is 10mg once daily, which can be taken regardless of meals. If blood pressure is not adequately controlled at this dose, it may be increased to 20mg once daily. If further blood pressure reduction is needed, the dose can be increased up to a maximum of 40mg once daily. The blood pressure-lowering effect appears within 2 weeks after starting treatment and reaches maximum effect in about 8 weeks.

Child dose

Safety and efficacy in pediatrics have not been established.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy; therefore, it should be stopped immediately upon confirmation of pregnancy. Individuals with allergies to this drug or its ingredients, pregnant or breastfeeding women, patients undergoing kidney dialysis, those with severe liver dysfunction, and patients with biliary obstruction should not take this drug. Patients with certain genetic disorders, such as lactose intolerance, should also avoid taking this drug. Those with low blood volume or salt may experience low blood pressure; therefore, they should consult their healthcare provider and monitor their condition closely. Caution is necessary for patients with severe heart failure or kidney function abnormalities as there is a risk of worsening kidney function. Patients with reduced kidney function should have regular blood tests to monitor potassium and creatinine levels. Patients with renal artery stenosis should also exercise caution as kidney function may worsen when taking this medication. There is a risk of hyperkalemia; therefore, especially patients with heart failure or kidney disorders should frequently check their serum potassium levels. Patients with aortic or mitral valve stenosis and hypertrophic obstructive cardiomyopathy should be cautious when using this medication. Patients with primary hyperaldosteronism are not recommended to take this drug due to inadequate response. Dizziness may occur during treatment, so driving or engaging in hazardous activities should be avoided. This medication may have a somewhat lesser blood pressure-lowering effect in Black patients. Although this drug is generally safe, side effects such as dizziness, headaches, back pain, dyspepsia, chest pain, peripheral edema, etc. can rarely occur. Abnormal reactions such as liver dysfunction or vascular edema, or increased blood pressure have also been reported. If abnormal symptoms occur, immediate consultation with a healthcare provider is necessary. If chronic diarrhea or significant weight loss occurs while taking this medication, chronic malabsorption syndrome should be suspected, prompting consultation with a doctor. Drug interactions may occur when taking other antihypertensive medications, potassium-sparing diuretics, lithium, and non-steroidal anti-inflammatory analgesics, so patients must inform their healthcare provider about all medications they are taking. Particularly, diabetic patients or those with reduced kidney function should avoid combining with aliskiren; if combined, blood pressure and kidney function should be monitored closely. Pregnant women should avoid this medication due to the serious risks to the fetus, and breastfeeding women should consider stopping the medication or breastfeeding due to potential effects on the infant. Safety in pediatrics has not been established, so use in children should be approached with caution. Elderly patients may require dose adjustments due to potential increases in drug concentration in the body. In cases of overdose, symptoms like hypotension, palpitations, and bradycardia may occur, and immediate treatment should be sought.

Serious side effects

Urticaria, angioedema, anaphylactic reactions, chronic malabsorption syndrome (sprue)-like enteropathy, intestinal vascular edema, rhabdomyolysis, hyperkalemia, acute kidney failure, elevated serum creatinine, urticaria, liver dysfunction (increased transaminases or total bilirubin), asthenia, angioedema, chest pain, peripheral edema, asthma

Mild side effects

• Dizziness
• headache
• palpitations
• back pain
• cough
• hematuria
• hyperglycemia
• hypertriglyceridemia
• flu-like symptoms
• pharyngitis

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 and 25 degrees Celsius to preserve the medication's effectiveness and safety.

Appearance

White, oblong film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle