Iteks Rosuvastatin Calcium Tablet 5mg

Adult dose

This medication can be administered at any time of the day, regardless of meals. The initial dose is 5 milligrams once daily, and if further LDL cholesterol reduction is needed, the maintenance dose can be adjusted accordingly. The maintenance dose is usually 10 milligrams once daily, which most patients are adjusted to. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or longer.

Child dose

The conventional dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years) is 5 milligrams to 20 milligrams once daily. The dosing should be tailored individually based on the recommended treatment goals for each patient.

This medication should not be used in certain patients. For instance, individuals allergic to the components of this medication, those with severely impaired liver function, those with muscle disorders, and those with severely impaired kidney function should not take this medication. Additionally, pregnant or breastfeeding women and women of childbearing age who are not using appropriate contraceptives should also avoid this medication. Patients who may be prone to muscle-related side effects should exercise caution, and high doses of this medication are contraindicated. This medication contains lactose, so individuals with lactose intolerance or related genetic disorders should not take it. Patients taking this medication should undergo regular liver function tests if they consume large amounts of alcohol or have a history of liver disease. Patients whose hypercholesterolemia is caused by hypothyroidism or nephrotic syndrome should treat the underlying conditions first. Muscle-related side effects such as myalgia, muscle weakness, myopathy, and rarely rhabdomyolysis may occur, so if any abnormal muscle symptoms arise during treatment, the physician should be informed immediately. If muscle injury markers are high in blood tests, medication may need to be discontinued. Patients with impaired kidney function or specific diseases should be monitored very carefully, and in cases of acute severe conditions, medication should be discontinued. This medication can rarely cause severe skin reactions, so if rash, itching, fever, or other symptoms appear, it should be stopped immediately and the medical staff consulted. Interactions with other medications may occur, so if other medications are being taken, this must be disclosed to the medical staff. The risk of muscle side effects may increase when used in conjunction with specific antibiotics, antifungal agents, immunosuppressants, or fibrate-class drugs. Pregnant women or those planning to become pregnant should not take this medication, and it should be stopped immediately if pregnancy occurs during treatment. Breastfeeding women are also advised to avoid this medication. In cases of overdose, there is no specific antidote, so treatment should be symptomatic and liver function and muscle damage should be assessed. Caution is advised when driving or operating machinery due to the possibility of dizziness. This medication may have higher systemic concentrations in Asians, necessitating dose adjustments. It is important to consult medical staff immediately if any unusual symptoms or suspected side effects occur during treatment.

Serious side effects

Angioedema (including swelling), severe allergic reactions, rhabdomyolysis, severe muscle weakness, ophthalmoplegia, severe skin adverse reactions (Stevens-Johnson syndrome, eosinophilia and systemic symptom drug reaction syndrome), jaundice, hepatitis, fatal and non-fatal liver failure, severe edema, acute kidney failure, oliguria, severe rash accompanied by high fever, blistering, skin peeling, pain in the oral/ocular mucosa, difficulty breathing

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• muscle weakness
• fatigue
• numbness

This medication should be stored in a tightly sealed container to protect it from air or moisture. It is important to maintain the storage temperature between 1 degree and 30 degrees Celsius. This ensures the safe maintenance of the medication's effectiveness.

Appearance

Yellow round film-coated tablets

Package unit

For domestic use - 30 tablets/bottle, for export - 30 tablets/box [10 tablets/(Alu-Alu X 3)]