Monorova Tablet 20 Milligrams (Rosuvastatin Calcium)

Adult dose

The medication is taken once daily at any time regardless of meals. The initial dose is 5 milligrams, and adjustments can be made at intervals of 4 weeks or more according to treatment goals. Generally, the maintenance dose is 10 milligrams, with a maximum increase to 20 milligrams.

Child dose

For pediatric patients aged 10 to 17 years, the dosage is 5 to 20 milligrams once daily. The dosage should be adjusted individually according to the treatment goals, and adjustments should be made at intervals of 4 weeks or more. For children under 10 years old, safety and efficacy have not been established.

This medication should not be used in certain patients. First, it should not be administered to patients with a known allergy to this medication, those with severely impaired liver function, patients with muscle disorders, and those with significantly reduced kidney function. Additionally, it should not be used by pregnant or nursing women, or women of childbearing age who are not using effective contraception. The 40 milligrams dosage is contraindicated for patients at high risk for muscle disorders. Caution should be exercised in patients who consume large amounts of alcohol or have a history of liver disease. Liver function tests should be repeated before and during administration, and any thyroid dysfunction or nephrotic syndrome should be treated prior. If symptoms such as myalgia, muscle weakness, or cramps occur during treatment, immediate medical attention should be sought. In particular, if there is a significant increase in muscle enzyme levels, the medication should be discontinued, and it can be restarted at a lower dose once symptoms improve. This medication may interact with certain drugs, so it is essential to consult a healthcare provider about any medications being taken concurrently. Particularly, concomitant use with certain antiviral agents, immunosuppressants, some antibiotics, and fibrate class drugs may increase the risk of muscle-related side effects. This medication should be avoided during pregnancy due to potential risks to the fetus, and it is also advisable to avoid use during lactation. In cases of overdose, there are no specific antidotes, so treatment should be symptomatic, and liver and muscle function tests are required. Patients may experience dizziness while on this medication; therefore, caution is advised when driving or operating machinery. Finally, this medication can rarely cause severe skin reactions, liver dysfunction, or muscle damage, so any abnormal symptoms should be reported to healthcare professionals immediately.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, breathing difficulties, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS) with elevated eosinophils and generalized symptoms, jaundice, hepatitis, severe liver failure, severe allergic reaction, severe skin reaction, rhabdomyolysis, immune-mediated necrotizing myopathy, ocular myasthenia gravis, severe muscle weakness, acute renal failure, oliguria, increased serum creatinine, and elevated blood pressure.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• hives
• myalgia
• malaise

This medication can be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is advisable to maintain a storage temperature between 1 to 30 degrees Celsius. This will help preserve the medication's effectiveness for an extended period.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle