Crechek Tablets 20 mg (Rosuvastatin Calcium)

Adult dose

This medication can be administered at any time of the day, regardless of meals. The initial dose is 5 mg once daily, and the maintenance dose is 10 mg once daily. The maintenance dose may be adjusted based on LDL cholesterol levels, treatment goals, and patient response, with maximum dosage up to 20 mg per day, typically adjusted at intervals of 4 weeks or more.

Child dose

In pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the usual dosage range is 5 mg to 20 mg once daily. The administered dose should be adjusted according to the treatment goals for each individual patient.

This medication should not be administered to certain patients. Patients with allergies to the ingredients of this medication, individuals with severely impaired liver function, those with muscle-related issues, and patients taking certain immunosuppressants should not use this medication. Additionally, patients with severely reduced kidney function, pregnant or nursing women, and women of childbearing age who do not use appropriate contraception should also avoid this medication. Patients at high risk of muscle disorders should particularly avoid taking high doses of this medication. This medication can affect liver function, so patients with liver disease or those who consume alcohol excessively should use it cautiously and undergo regular liver function tests. If symptoms such as muscle pain or weakness occur, they should inform their doctor immediately, and discontinuation of the medication may be necessary. Patients with reduced kidney function, hypothyroidism, the elderly, and those who abuse alcohol should pay more attention to muscle side effects. Rarely, this medication may cause side effects such as headaches, dizziness, dyspepsia, skin rash, muscle pain, and muscle weakness, and there have been reports of serious side effects such as severe liver damage or muscle rupture. Therefore, if unusual symptoms persist or worsen, immediate consultation with medical professionals is necessary. This medication can interact with other drugs, so if you are taking other medications, make sure to inform your doctor or pharmacist. Caution is needed when used with certain antiviral drugs, immunosuppressants, antibiotics, and fibrate-class medications, as this may increase the risk of muscle side effects. Pregnant women or those planning to become pregnant should not take this medication, and if pregnancy is confirmed during use, it should be discontinued immediately. Nursing mothers are also advised not to use this medication. In case of overdose, there is no specific antidote, so treatment should be symptomatic and liver function and muscle enzyme tests should be performed. This medication is not known to significantly affect driving or machine operation, but caution is advised due to the possibility of dizziness. Always consult a doctor or pharmacist before taking this medication to ensure safe usage.

Serious side effects

Allergic reactions including angioedema, pancreatitis, myopathy (including myositis), rhabdomyolysis, polyneuropathy, severe muscle weakness, respiratory distress, oculomotor muscle weakness, thrombocytopenia, jaundice, hepatitis, Stevens-Johnson syndrome, eosinophilia accompanied by systemic symptoms (DRESS), immune-mediated necrotizing myopathy, acute renal failure, oliguria, increased serum creatinine, edema, fatal and non-fatal liver failure

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• hives
• muscle pain
• weakness

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The best storage temperature is between 1 to 30 degrees Celsius at room temperature to maintain its efficacy and safety over time.

Appearance

Pink round film-coated tablets

Package unit

28 tablets (14 tablets/PTP packaging x2), 30 tablets/bottle