Medication info
Raviem Tablet 10 mg (Rabeprazole Sodium)

Raviem Tablet 10 mg (Rabeprazole Sodium)

Prescription medicationTablet경구
Ingredient · strength
Rabeprazole Sodium›10mg / 1 tablet
Manufacturer / importer
구주제약(주)
Appearance
Light yellow round enteric-coated tablet
Packaging
28 tablets (14 tablets/AluAlu packaging * 2)
Approval status
Active

MFDS item code 201310978 · Approved 2013.12.31 · Insurance code 669804320

Summary

Main use
Treatment of gastric ulcers and duodenal ulcers, alleviation of gastroesophageal reflux disease symptoms, etc.
Who takes it
Adults
Adult dose
Gastric ulcer, duodenal ulcer: Usually, 10 mg of rabeprazole sodium is administered orally once daily to adults. Depending on symptoms, it may be increased to 20 mg once daily. Typically, treatment is up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If treatment is ineffective after 8 weeks of proton pump inhibitors (PPIs), an additional 8 weeks of 10 mg or 20 mg may be administered twice daily. However, dosing of 20 mg twice daily is reserved for patients with confirmed severe mucosal injury. Symptom relief of gastroesophageal reflux disease: Administer 10 mg once daily. If symptoms are not controlled after 4 weeks, further evaluation is necessary. Once symptoms have resolved, on-demand therapy may be used with 10 mg once daily as needed to control any subsequent symptoms. Long-term maintenance therapy for gastroesophageal reflux disease: Administer 10 mg or 20 mg orally once daily depending on the patient. Helicobacter pylori eradication: Patients infected with Helicobacter pylori should undergo eradication therapy. It is recommended to combine this medication 20 mg with clarithromycin 500 mg and amoxicillin 1 g, taken twice daily for 7 days. Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg once daily. The dosage may be adjusted up to 120 mg as per individual patient needs. Doses up to 100 mg may be administered once daily, while 120 mg should be divided into 60 mg taken twice daily. Patients with Zollinger-Ellison syndrome have been treated with this medication for up to one year. ○ In case of liver impairment: Adverse reactions of hepatic encephalopathy have been reported in patients with cirrhosis, so administer with caution. ○ In pediatric patients: Safety has not been established in children. ○ In elderly patients: Administer with caution as liver function is often impaired.

Ingredients

Manufacturer
구주제약(주)

Efficacy & effects

Treatment of gastric ulcers and duodenal ulcers, alleviation of gastroesophageal reflux disease symptoms, etc.

  • Gastric ulcer
  • duodenal ulcer
  • erosive gastroesophageal reflux disease
  • ulcerative gastroesophageal reflux disease
  • symptoms of gastroesophageal reflux disease
  • gastrointestinal ulcers
  • Zollinger-Ellison syndrome
View approved original text

This medication is used for the treatment of gastric ulcers and duodenal ulcers and is effective in alleviating symptoms of erosive or ulcerative gastroesophageal reflux disease. It is also suitable for long-term maintenance therapy of gastroesophageal reflux disease and is used in combination with antibiotics for the treatment of gastric ulcer patients infected with Helicobacter pylori. It is also used for rare conditions of excessive gastric acid secretion such as Zollinger-Ellison syndrome. Overall, it helps improve inflammation and ulcers in the stomach and esophagus.

How to take

Adult dose

Gastric ulcer, duodenal ulcer: Usually, 10 mg of rabeprazole sodium is administered orally once daily to adults. Depending on symptoms, it may be increased to 20 mg once daily. Typically, treatment is up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If treatment is ineffective after 8 weeks of proton pump inhibitors (PPIs), an additional 8 weeks of 10 mg or 20 mg may be administered twice daily. However, dosing of 20 mg twice daily is reserved for patients with confirmed severe mucosal injury. Symptom relief of gastroesophageal reflux disease: Administer 10 mg once daily. If symptoms are not controlled after 4 weeks, further evaluation is necessary. Once symptoms have resolved, on-demand therapy may be used with 10 mg once daily as needed to control any subsequent symptoms. Long-term maintenance therapy for gastroesophageal reflux disease: Administer 10 mg or 20 mg orally once daily depending on the patient. Helicobacter pylori eradication: Patients infected with Helicobacter pylori should undergo eradication therapy. It is recommended to combine this medication 20 mg with clarithromycin 500 mg and amoxicillin 1 g, taken twice daily for 7 days. Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg once daily. The dosage may be adjusted up to 120 mg as per individual patient needs. Doses up to 100 mg may be administered once daily, while 120 mg should be divided into 60 mg taken twice daily. Patients with Zollinger-Ellison syndrome have been treated with this medication for up to one year. ○ In case of liver impairment: Adverse reactions of hepatic encephalopathy have been reported in patients with cirrhosis, so administer with caution. ○ In pediatric patients: Safety has not been established in children. ○ In elderly patients: Administer with caution as liver function is often impaired.

Precautions

This medication should not be used by patients who are allergic to specific ingredients or have a history of hypersensitivity. Caution is necessary when combining with antibiotics from the penicillin or macrolide classes in patients who have allergies to these. Pregnant or breastfeeding women should not take this medication. Patients with impaired liver function, elderly individuals, or those with a history of drug allergies should take it with caution. This medication contains Yellow No. 4 dye, so individuals sensitive to this ingredient should be cautious. If rash, urticaria, or itching occurs during use, discontinue taking the medication immediately. Regular blood tests are required as red blood cell or white blood cell counts may change. Liver function tests should also be periodically conducted as liver dysfunction may occur. Patients with cardiovascular diseases should be careful as it may affect the heart and blood vessels. Symptoms such as diarrhea, abdominal pain, and nausea may occur, so pay attention to these symptoms. Neurological side effects such as headaches, dizziness, and insomnia have also been reported, requiring caution during use. Respiratory symptoms or skin rashes and itching may appear, so consult a doctor if unusual symptoms occur. Long-term use of this medication may increase the risk of fractures related to osteoporosis, so caution is necessary for prolonged use. Hypomagnesemia may occasionally occur, so magnesium levels should be monitored during prolonged use or when used in combination with certain medications. This medication can slightly increase the risk of bacterial infections in the stomach by suppressing gastric acid, so inform your doctor if diarrhea persists. There may be drowsiness when driving or operating machinery, requiring caution. Drug interactions may occur, so inform your doctor or pharmacist of any other medications being taken. This medication should be swallowed whole without chewing or breaking, and stored out of reach of children.

Side effects and when to seek care immediately

Serious side effects

Urticaria, tightness in the chest, difficulty breathing, jaundice, sudden and very severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output, severe swelling throughout the body, accompanied by increased blood pressure, severe swelling (edema), severe allergic reactions, severe skin reactions, asthma attacks, respiratory problems accompanied by cough and fever, yellowing of the skin or eyes, extreme lethargy, severe

Mild side effects

  • Rash
  • itching
  • decreased red blood cells
  • decreased white blood cells
  • increased white blood cells
  • increased eosinophils
  • increased neutrophils
  • decreased lymphocytes
  • anemia
  • petechial hemorrhage
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  • lymphadenopathy
  • hypochromic anemia
  • pancytopenia
  • agranulocytosis
  • decreased platelets
  • hemolytic anemia
  • increased ALT
  • increased AST
  • increased ALP
  • increased γ-GTP
  • increased LDH
  • increased total bilirubin
  • hypertension
  • myocardial infarction
  • abnormal electrocardiogram
  • migraine
  • syncope
  • angina
  • heart block
  • palpitations

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is advisable to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. This will help maintain the drug's efficacy and safety over time.

Appearance and packaging

Appearance

Light yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/AluAlu packaging * 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.