Subast Tablet 5mg (Rosuvastatin Calcium)

Adult dose

This medication can be taken at any time of day, with or without food. The initial dose is 5mg once daily, and if more reduction of LDL-cholesterol is needed, the maintenance dose can be adjusted. The maintenance dose is typically 10mg once daily, and most patients are titrated to this dose. Dosage adjustments should be made every 4 weeks or longer based on LDL-cholesterol levels, treatment goals, and patient response.

Child dose

The usual dose range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 5mg to 20mg once daily. The dosage should be adjusted according to the recommended treatment goals for individual patients.

This medication should not be used in certain patients. For example, patients who are allergic to this medication or who have severely impaired liver function should not take it. Additionally, patients with muscular diseases or severe renal impairment, as well as pregnant or breastfeeding women, should not take this medication. Women of reproductive potential should only be administered after counseling on appropriate contraception to reduce the possibility of pregnancy. Particular caution must be exercised when using this medication in patients at high risk of muscle-related side effects. For instance, patients with moderate to severe renal impairment, hypothyroidism, a family history of muscle disorders, alcohol dependence, and certain ethnicities (such as Asians) should be extra careful. Also, the risk of muscle side effects may increase when taken with certain other medications, so it is important to consult a physician. This medication contains lactose, so it should not be administered to patients with lactose intolerance or related genetic disorders. It is important to regularly monitor liver function and muscle status during treatment. If abnormal elevations in liver enzyme levels, muscle pain, or muscle weakness occur, the patient must notify their physician immediately. This medication may cause rare side effects such as interstitial lung disease, severe liver injury, and severe skin reactions, so if symptoms such as shortness of breath, rash, or jaundice occur, treatment should be discontinued and medical advice sought immediately. This medication can interact with other drugs, so if the patient is taking any other medications, they must inform their physician or pharmacist. Extra caution is needed when taken with medications that could raise the risk of muscle damage. Pregnant or nursing women should not use this medication, and women planning pregnancy should use appropriate birth control methods. In cases of overdose, there is no specific antidote, so treatment should be based on symptoms, and liver function and muscle enzyme levels must be monitored. This medication is known not to have a significant effect on driving or machinery operation, but dizziness may be a concern, so caution is needed.

Serious side effects

Allergic reactions including urticaria and angioedema, chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe myopathy, ophthalmoplegia, rhabdomyolysis, immune-mediated necrotizing myopathy, thrombocytopenia, acute kidney injury, oliguria, severe rash with fever, blistering, skin desquamation, mucosal pain in mouth/eyes, severe swelling

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• thrombocytopenia
• diarrhea

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is best kept at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness for a longer period.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/box [15 tablets/PTPX2], 300 tablets/bottle