Omecl 375 mg (Amoxicillin Hydrate & Potassium Clavulanate (2:1))

Adult dose

For adults and children aged 12 years or older or weighing 40 kg or more, the standard dosage is 250 mg/125 mg of amoxicillin/clavulanate potassium taken orally three times a day every 8 hours, with possible increase to 500 mg/125 mg for severe and respiratory infections. In cases of renal impairment, the dosage should be adjusted according to creatinine clearance. - Creatinine clearance of 30 mL/min or more: no dosage adjustment necessary.

Child dose

For children under 12 years old or weighing less than 40 kg, the dosage should be reduced and administered similarly to adults.

This medication is a beta-lactam antibiotic that belongs to the penicillin group and should not be administered to certain patients. For example, patients with allergies to this medication or beta-lactam drugs, those with a history of hypersensitivity, patients with viral infections such as infectious mononucleosis or lymphocytic leukemia, and those who have experienced liver dysfunction due to this medication or penicillin should not use it. Patients with poor liver function or moderate to severe renal impairment should use this medication with caution, and those with allergies, difficulties swallowing orally, elderly patients, and patients in poor general condition should also be careful. Additionally, patients with gastrointestinal diseases presenting with vomiting or diarrhea should exercise caution as drug absorption may be impaired. While taking this medication, gastrointestinal adverse reactions such as diarrhea, gastrointestinal disturbances, vomiting, and loss of appetite may occur. Rarely, elevations in liver function tests or liver diseases such as hepatitis and jaundice may occur. Skin rashes or itching have been reported, and in severe cases, serious skin reactions such as Stevens-Johnson syndrome may occur. If skin abnormal symptoms appear during treatment, consult a doctor immediately. Moreover, rare blood-related abnormalities such as leukopenia, thrombocytopenia, and anemia may occur. Rarely, renal function impairment and central nervous system symptoms may arise, thus caution is required. Prolonged use of this medication may lead to a tendency to bleed due to vitamin K deficiency, necessitating regular checks. This medication may interact with other drugs; therefore, it is essential to inform the doctor or pharmacist, especially when used in conjunction with anticoagulants or certain antibiotics and anti-inflammatory drugs. Women who are pregnant or breastfeeding must consult a healthcare professional before use, and it is better to avoid administration in the early stages of pregnancy. In cases of overdose, gastrointestinal symptoms may manifest, along with renal failure or neurological disturbances, so if suspected, visit a medical facility immediately for appropriate treatment. This medication should be stored in a specially sealed container to prevent moisture, and it should be maintained at a cool temperature between 1°C and 25°C. By adhering to these storage guidelines, the medication's efficacy and safety can be preserved for an extended period.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, high fever accompanied by severe rash, blisters, skin peeling, pain in oral/eye mucosa, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory issues accompanied by coughing and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and very severe

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• black hairy tongue
• nausea
• vomiting
• loss of appetite

This medication is stored in a specially sealed container to prevent moisture, and while storing, it should be maintained at a cool temperature between 1°C and 25°C. By keeping it this way, the drug's effectiveness and safety can be maintained for a long time.

Appearance

White or almost white oval film-coated tablet

Package unit

100 tablets (10 tablets/PTP packaging x 10)