Lobetin Tablet 10mg (Rosuvastatin Calcium)

Adult dose

This medication can be taken any time of the day, regardless of meals. The initial dose is 5 mg once daily; for those needing more significant reductions in LDL-cholesterol levels, it can be adjusted to a maintenance dose. The maintenance dose is typically 10 mg once daily, which most patients are regulated at. The maintenance dosage should be adjusted appropriately based on LDL-cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more.

Child dose

The usual dosage range is 5 mg to 20 mg once daily. The dosage should be adjusted according to individual treatment goals at intervals of 4 weeks or more.

This medication should not be used in certain patients. For example, it should not be administered to patients with allergies to this drug, severely impaired liver function, muscle disorders, or those taking certain immunosuppressants. Women who are pregnant or breastfeeding should not take this medication and women of childbearing age should use appropriate contraception. Additionally, since this medication can cause muscle-related side effects, any symptoms of muscle pain or weakness should be reported to healthcare professionals immediately. Special caution is needed in patients with poor renal function, low thyroid function, the elderly, and those who consume excessive alcohol. Patients on this medication should have regular liver function tests, and should discontinue use if symptoms of liver damage appear. This medication can interact with various medications, so patients taking other medications should inform their healthcare providers, especially when taking certain antivirals, immunosuppressants, or fibrate-class medications. In case of an overdose, as there is no specific antidote, treatment should be symptomatic, and liver function and muscle enzyme levels should be monitored. Caution should be exercised while driving or operating machinery as dizziness may occur. Finally, this medication may show higher blood concentrations in Asians, thus dosage adjustment may be necessary.

Serious side effects

Allergic reactions including hives, angioedema, pancreatitis, myopathy, rhabdomyolysis, polyneuropathy, memory loss, peripheral neuropathy, severe muscle weakness, dyspnea, ophthalmoplegia, thrombocytopenia, jaundice, hepatitis, increased transaminases, Stevens-Johnson syndrome, eosinophilia, and drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, edema, acute renal failure, oliguria, blood dyscrasia

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• diarrhea
• chest discomfort

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is best to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness for a longer duration.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle