Anicra Tablet 625 mg (Amoxicillin Hydrate - Potassium Clavulanate (4:1))

Adult dose

Adults and children 12 years and older or weighing 40 kg or more should take Amoxicillin/Clavulanate Potassium at a dose of 250 mg/125 mg 3 times a day every 8 hours. In severe cases and respiratory infections, the dose can be increased to 500 mg/125 mg. In cases of renal impairment, the dosage should be adjusted according to creatinine clearance. - Creatinine clearance above 30 mL/min: No dosage adjustment required.

Child dose

Dosage for children under 12 years of age or weighing less than 40 kg should be reduced accordingly.

This medication should not be administered to patients with hypersensitivity to specific ingredients or beta-lactam antibiotics. Patients with viral infections such as infectious mononucleosis or lymphocytic leukemia are at increased risk of rash; caution is required. It is advisable not to use this medication in patients who have previously experienced liver dysfunction or jaundice due to this medication or penicillin-class drugs. In patients with impaired liver function, use with caution as the drug may worsen liver function. In patients with moderate to severe renal impairment, dosing intervals should be adjusted as drug concentrations may increase. Patients with allergic tendencies or family histories may have severe reactions to the medication and should be monitored closely. Patients who have difficulty with oral intake or poor nutritional status, especially the elderly, should take caution due to the risk of bleeding from vitamin K deficiency. Patients with gastrointestinal diseases with vomiting or diarrhea may not absorb the medication properly. This medication can cause gastrointestinal side effects such as diarrhea, gastroenteritis, and vomiting, and in severe cases, pseudomembranous colitis may occur, so consultation with a doctor should occur immediately if symptoms appear. Symptoms of liver dysfunction have been rarely reported, especially in the elderly and males, so liver function testing may be necessary. Skin rashes, hives, and severe allergic reactions may occur, and if these symptoms arise, medication should be discontinued and physician's instructions followed. Hematological side effects, such as leukopenia and anemia, have been rarely reported, necessitating regular blood tests. Central nervous system reactions, such as anxiety, drowsiness, and seizures, can occur rarely, so any unusual symptoms should be reported. Renal function may deteriorate, so renal function tests should be performed to monitor the condition. This medication may interact with other drugs, so if you are taking any other medications, you must inform your healthcare provider. Pregnant or nursing women should use this medication cautiously and it is particularly advised not to use during the first three months of pregnancy. Usage in children, particularly those under 12 years of age or weighing less than 40 kg, is not recommended. Elderly patients may experience abnormal reactions more frequently due to diminished physiological function, so dosage and administration intervals should be adjusted and monitored closely. In cases of overdose, gastrointestinal symptoms, renal failure, and seizures may occur, necessitating immediate contact with a healthcare provider. This medication should be stored in a dried place below 25 degrees Celsius, and the safe usage period does not exceed 14 days, depending on the indications.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reaction, severe rash with high fever, blistering, skin peeling, pain in oral/ocular mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of skin or eyes, jaundice, generalized extreme fatigue, liver dysfunction, sudden and severe headache, lightning pains.

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• black hairy tongue
• nausea
• vomiting
• anorexia

This medication is contained in a sealed container to protect it from moisture and air. When storing, it is advised to keep it in a cool place with a temperature between 1 and 25 degrees Celsius. This helps maintain the effectiveness of the medication and prevents deterioration.

Appearance

This medication is a white or almost white oblong film-coated tablet.

Package unit

40 tablets/PTP