Hericlo Tablet 500 mg (Clarithromycin)

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal impairment and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this drug twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this drug 3 times daily for 14 days together with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used in certain patients. For example, patients with allergies to the components of this drug or those who have hypersensitivity to certain antibiotics should not be administered this drug. Patients with cardiac rhythm problems or severe liver or kidney dysfunction should also avoid using this medication. Additionally, pregnant or nursing women should not take this drug. This medication can interact with other drugs, so patients taking specific medications should consult their doctor or pharmacist. Caution is needed when taking this medication with drugs that may affect the heart, certain antibiotics, or medications that affect blood coagulation. When using this medication, patients should carefully observe for allergic reactions or severe side effects, and if any abnormal symptoms occur, they should immediately stop using it and consult a healthcare professional. Furthermore, this medication can cause various side effects such as gastrointestinal disturbances, liver function abnormalities, kidney issues, and central nervous system symptoms, so regular monitoring may be necessary. Children, elderly patients, and those with impaired liver or kidney function may require dosage adjustments or special precautions when using this medication. In case of overdose, symptoms such as gastrointestinal disturbances or psychiatric symptoms may occur, so doses should be strictly adhered to, and in case of overdose, patients should visit a medical facility for appropriate treatment. Finally, this medication should be stored away from direct sunlight and at room temperature, and refrigeration is not recommended.

shock, anaphylactic symptoms, difficulty breathing, convulsions, flushing, rash, itching, hives, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disturbance, decreased appetite, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucination, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, cytotoxic hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, dysgeusia, hearing loss, paraesthesia, arthralgia, myalgia, olfactory dysfunction, hypoglycemia, tinnitus, auditory impairment, purpuric rash, acute generalized pustular psoriasis, muscle cramps, musculoskeletal rigidity, myopathy, elevated blood creatinine, increased blood urea, nephritis, venous inflammation at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, increased serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, urine discoloration, vasodilation, asthma, nasal bleeding, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration

This medication is sensitive to light, so it should be stored in a light-resistant container. Additionally, it is advisable to keep the medication at room temperature between 15°C and 30°C to maintain its efficacy.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle