Medication info
Actosril 30/4 mg tablet

Actosril 30/4 mg tablet

Prescription medicationTablet경구
Ingredient · strength
Pioglitazone Hydrochloride›33.06mg / 1 tabletGlimepiride›4mg / 1 tablet
Manufacturer / importer
(주)셀트리온제약
Appearance
White to grayish-white, convex round tablets
Packaging
28 tablets (14 tablets/PTP packaging x 2)
Approval status
Active

MFDS item code 201309845 · Approved 2013.10.21 · Insurance code 693903500

Summary

Main use
Improvement of blood sugar control in type 2 diabetes
Who takes it
Adults
Adult dose
The dosage of this medication should be individualized based on the patient's efficacy and tolerance. This medication should be taken once daily with breakfast. For patients whose blood sugar is not adequately controlled with glimepiride monotherapy, pioglitazone 15 mg can be combined with glimepiride, and after evaluating the treatment response, either pioglitazone/glimepiride 30 mg/2 mg tablet or 30 mg/4 mg tablet can be administered once daily.

Ingredients

Importer
(주)셀트리온제약

Efficacy & effects

Improvement of blood sugar control in type 2 diabetes

View approved original text

This medication is used as an adjunct to diet and exercise to improve blood glucose control in patients with type 2 diabetes who are appropriate candidates for combined therapy with glimepiride and pioglitazone.

How to take

Adult dose

The dosage of this medication should be individualized based on the patient's efficacy and tolerance. This medication should be taken once daily with breakfast. For patients whose blood sugar is not adequately controlled with glimepiride monotherapy, pioglitazone 15 mg can be combined with glimepiride, and after evaluating the treatment response, either pioglitazone/glimepiride 30 mg/2 mg tablet or 30 mg/4 mg tablet can be administered once daily.

Precautions

This medication is used to treat type 2 diabetes and helps lower blood sugar levels. However, this medication should not be used in patients with severe heart function impairment, as it may present risks of worsening symptoms of heart failure. During treatment, if symptoms such as rapid weight gain or shortness of breath appear, consult a doctor immediately. Patients with a history of bladder cancer should carefully compare the risks of cancer recurrence with the benefits of blood glucose control when using this medication. Women who are pregnant or breastfeeding should avoid taking this medication, and pre-menopausal women are advised to use adequate contraception, as this medication may stimulate ovulation. This medication can affect liver function; therefore, regular liver function tests should be conducted before and during treatment, and if any signs of liver damage appear, notify medical personnel immediately. Due to the risk of hypoglycemia, particularly when co-administered with other glucose-lowering agents, it is important to be aware of hypoglycemic symptoms and to maintain regular eating and drinking habits. Elderly patients and those with impaired renal function have a higher risk of hypoglycemia, so careful dosage adjustments and monitoring are essential. Regular blood glucose and glycosylated hemoglobin tests should be conducted to check glucose control status while taking this medication, and if any unexpected side effects occur, consult a doctor immediately.

Side effects and when to seek care immediately

Serious side effects

Congestive heart failure, severe edema, chest tightness, difficulty breathing, hypoglycemia, hives, angioedema, Stevens-Johnson syndrome, dyspnea, severe allergic reactions, liver function abnormalities (jaundice), symptoms of liver damage (fatigue, loss of appetite, right upper quadrant discomfort, dark urine, jaundice), severe neurological symptoms (seizures, confused consciousness, visual disturbances, paralysis), severe edema or urinary abnormalities (visible hematuria, urinary disturbances, urgency)

Mild side effects

  • Upper respiratory tract infection
  • accidental injury
  • combined edema/peripheral edema
  • hypoglycemia
  • weight gain
  • lower limb edema
  • headache
  • urinary tract infection
  • diarrhea
  • nausea
Show 19 more
  • limb pain
  • myalgia
  • dental disturbances
  • worsening diabetes
  • pharyngitis
  • anemia
  • dizziness
  • weakness
  • vomiting
  • gastrointestinal pain
  • increased liver enzyme levels
  • itching
  • erythema
  • rash
  • changes in lens accommodation
  • blurred vision
  • thrombocytopenia
  • thrombocytopenic purpura
  • failure to control blood sugar

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture, ideally at room temperature between 1 and 30 degrees Celsius. This storage method helps maintain the medication's efficacy and safety.

Appearance and packaging

Appearance

White to grayish-white, convex round tablets

Package unit

28 tablets (14 tablets/PTP packaging x 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.