Medication info
Moxifloxacin 400mg Tablet (Moxifloxacin Hydrochloride)

Moxifloxacin 400mg Tablet (Moxifloxacin Hydrochloride)

Prescription medicationTablet경구
Ingredient · strength
Moxifloxacin Hydrochloride›436.8mg / 1 tablet
Manufacturer / importer
한미약품(주)
Appearance
Dark pink oblong film-coated tablet
Packaging
30 tablets/box [5 tablets/PTP x 6]
Approval status
Active

MFDS item code 201309618 · Approved 2013.10.10 · Insurance code 643506700

Summary

Main use
Treatment of respiratory infections (acute sinusitis, exacerbation of chronic bronchitis), skin and soft tissue infections
Who takes it
Adults
Adult dose
As moxifloxacin, take 400 mg once daily with plenty of water without regard to meals. No dosage adjustment is necessary for patients with renal impairment. The duration of administration should be determined according to the severity of the infection or clinical response, with recommended durations as follows: acute sinusitis 7 days, acute exacerbation of chronic bronchitis 5 days, community-acquired pneumonia 10 days, uncomplicated skin and soft tissue infections 7 days, sequential therapy for complicated skin and soft tissue infections 7 to 21 days.

Ingredients

Manufacturer
한미약품(주)

Efficacy & effects

Treatment of respiratory infections (acute sinusitis, exacerbation of chronic bronchitis), skin and soft tissue infections

  • Acute sinusitis
  • acute exacerbation of chronic bronchitis
  • community-acquired pneumonia
  • skin and soft tissue infections
  • complicated intra-abdominal infections
  • uncomplicated pelvic infections
View approved original text

This drug is effective against various types of bacteria and can be used for respiratory infections such as acute sinusitis, acute exacerbation of chronic bronchitis, and community-acquired pneumonia. It is also applicable for the treatment of skin and soft tissue infections, intra-abdominal infections, and uncomplicated pelvic infections. Particularly, since it belongs to the fluoroquinolone class of drugs, it should only be used in cases where there are no other treatment options available for acute bacterial sinusitis and bacterial exacerbation of chronic bronchitis, considering the potential for serious adverse reactions. It has a broad spectrum of antimicrobial activity against various Gram-positive bacteria, Gram-negative bacteria, anaerobes, and atypical bacteria, providing assistance in the treatment of diverse infections. This drug is effective for the treatment of infections, so it should be used cautiously to improve infection symptoms.

How to take

Adult dose

As moxifloxacin, take 400 mg once daily with plenty of water without regard to meals. No dosage adjustment is necessary for patients with renal impairment. The duration of administration should be determined according to the severity of the infection or clinical response, with recommended durations as follows: acute sinusitis 7 days, acute exacerbation of chronic bronchitis 5 days, community-acquired pneumonia 10 days, uncomplicated skin and soft tissue infections 7 days, sequential therapy for complicated skin and soft tissue infections 7 to 21 days.

Precautions

This drug may cause problems with tendons, such as tendonitis or tendon rupture; therefore, if such symptoms occur, the medication should be discontinued immediately. Additionally, peripheral neuropathy or central nervous system adverse reactions may occur, so consult a physician immediately if neurological symptoms arise. Patients with myasthenia gravis should not use this drug as their symptoms may worsen. This medication is only used to treat specific bacterial infections and should only be administered when there are no other treatment options available for safety. The risk of tendon rupture is particularly high in the elderly, corticosteroid users, and patients who have undergone kidney, heart, or lung transplantation, so caution is required. In cases of tendonitis or rupture, rest should be taken, strenuous exercise should be avoided, and the medication should be discontinued. This drug may precipitate or exacerbate seizures, so patients with central nervous system disorders should use it cautiously. If there are issues with liver function or symptoms of hepatitis, the medication should be discontinued immediately and medical consultation sought. It is not recommended for use in pregnant women or breastfeeding mothers, or in children under 18. Patients with heart disease or a history of electrolyte imbalances or arrhythmias should consult a doctor before taking this medication. This drug may cause fluctuations in blood sugar, so diabetic patients need to carefully monitor their blood sugar and report any abnormal symptoms immediately. If an allergic reaction occurs during medication, such as skin rash, hives, or difficulty breathing, the medication should be stopped immediately and the healthcare provider notified. It is advisable to avoid excessive sun exposure while taking this medication. There may be interactions with other drugs, so individuals taking other medications should inform their healthcare provider and maintain intervals between doses, especially with antacids, calcium, and iron supplements. In case of overdose, seek medical advice immediately and obtain appropriate treatment. Store this drug out of reach of children and do not transfer it to another container for safety.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reaction) High fever accompanied by severe rashes, blisters, skin peeling, pain in mucous membranes of mouth/eyes (severe skin adverse reactions) Difficulty breathing or breathing difficulty, asthma attacks, respiratory abnormalities with cough and fever Yellowing of skin or eyes (jaundice), profound lethargy (liver abnormalities) Sudden and severe headaches.

Mild side effects

  • Nausea
  • vomiting
  • diarrhea
  • headache
  • dizziness
  • muscle pain
  • joint pain
  • anxiety
  • psychomotor hyperactivity
  • depression
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  • hallucinations
  • tinnitus
  • hearing loss
  • decreased appetite
  • indigestion
  • abdominal pain
  • constipation
  • swallowing difficulties
  • stomatitis
  • antibiotic-associated colitis
  • jaundice
  • increased bilirubin
  • hepatitis
  • elevated amino-transferases
  • fever
  • chest pain
  • tremors
  • alopecia
  • swelling
  • injection site reactions
  • shaking
  • drowsiness
  • coordination impairment
  • amnesia
  • speech disorders
  • decreased concentration.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air exposure, maintaining storage temperature between 1 degrees to 30 degrees Celsius. Proper storage will help preserve the drug's effectiveness.

Appearance and packaging

Appearance

Dark pink oblong film-coated tablet

Package unit

30 tablets/box [5 tablets/PTP x 6]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.