Abilify ODT 10 mg (Aripiprazole)

Adult dose

1. Schizophrenia - The recommended initial dose is 10 mg or 15 mg once daily, irrespective of meals. - For the treatment of schizophrenia, the dose can be adjusted in the range of 10-30 mg daily. - Maintenance therapy is administered at a dose of 15 mg daily for more than 3 months. 2. Treatment of mania and mixed episodes related to bipolar disorder - The recommended initial dose is 15 mg once daily, irrespective of meals. - Subsequent doses and adjustments will conform to clinical response.

Child dose

1. Schizophrenia in adolescents (ages 13-17) - Recommended dosage is 10 mg daily, irrespective of meals. - The initial dosage is 2 mg daily, which is increased to 5 mg after 2 days, and then to 10 mg again after another 2 days.

This medication may increase the risk of suicidal thoughts or behaviors in children, adolescents, and young adults with major depressive disorder or other psychiatric illnesses; therefore, physicians should carefully weigh the risks and benefits when prescribing this medication. All patients taking this medication should be closely monitored for worsening depression, suicidal tendencies, or unusual behavior changes, and family members or caregivers should also monitor the patient and report any concerns to a physician. This medication is not approved for treating depression in children and should not be used in this population. Serious adverse effects known as neuroleptic malignant syndrome may occur with this medication, presenting with high fever, muscle rigidity, changes in mental status, unstable blood pressure and pulse; if these symptoms occur, immediate medical attention should be sought. Long-term use of this medication may lead to tardive dyskinesia, an involuntary abnormal movement disorder, especially in the elderly or women, making it crucial to use the minimum effective dose for the shortest duration necessary. In elderly patients with dementia-related psychosis, the use of this drug may increase the risk of cerebrovascular accidents such as strokes and mortality; therefore, it should not be used for treating dementia-related psychosis. This medication may elevate blood sugar levels, so diabetic patients should regularly monitor their blood glucose control, as should individuals with risk factors for diabetes. This medication carries a risk for venous thromboembolism during treatment; individuals with thrombotic risk factors should consult their physician and take preventive measures. This drug contains the artificial sweetener aspartame and is contraindicated for patients with phenylketonuria. Patients with hypersensitivity or lactose intolerance should not use this medication, and those with orthostatic hypotension, a history of seizures, or impaired cognitive or motor abilities should use it cautiously. Symptoms such as worsening depression, suicidal tendencies, anxiety, agitation, aggression, and insomnia may occur during the initial treatment or with dose adjustments; close monitoring is required. This medication may cause drowsiness or dizziness, necessitating caution when driving or operating hazardous machinery. Weight gain, gastrointestinal discomfort, headache, tremor, insomnia, anxiety, among other side effects may occur; any prolonged symptoms should be discussed with a physician. Regular check-ups and monitoring are necessary since involuntary movement symptoms, muscle rigidity, and blood pressure changes may develop while on this medication.

Serious side effects

Rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headache, lightning-like headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Nausea
• vomiting
• constipation
• headache
• dizziness
• akathisia
• anxiety
• insomnia
• restlessness
• drowsiness

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. It is recommended to store it at room temperature between 1°C and 30°C. Proper storage will maintain the medication's effectiveness and ensure its safe use.

Appearance

Round tablet with pink speckles (imprint A640, 10)

Package unit

30 tablets (10 tablets/PTP x 3)