Rapuzin Tablets (Lafutidine)

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose of lafutidine is 10mg orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks, although healing time may occasionally vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose of lafutidine is 10mg orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks, although healing time may occasionally vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose of lafutidine is 10mg orally once daily before bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks, although healing time may occasionally vary from patient to patient. 4. Combination therapy with antibiotics for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Preanesthetic medication: The usual dose is lafutidine 10mg per dose, taken orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg per dose orally twice daily.

This drug should not be used in patients who are allergic to any of its ingredients. Additionally, this drug contains lactose, so patients with genetic issues such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should avoid taking it. Patients who have had hypersensitivity to the drug, as well as those with liver or kidney function issues, those undergoing dialysis, and the elderly should use this drug with caution. This drug can rarely cause severe allergic reactions, so if symptoms like facial paleness, drop in blood pressure, or difficulty breathing occur, discontinue use immediately and inform medical personnel. Liver function may deteriorate or jaundice symptoms may appear, so regular liver function tests are necessary to monitor the condition. Moreover, this drug can affect blood cell counts, so if symptoms like pharyngalgia, body weakness, or fever appear, immediate consultation with medical personnel is advised. Additionally, various side effects such as skin rashes, seizures, nephritis, and heart problems have been reported, so it is crucial to inform a doctor of any unusual symptoms. In clinical trials, gastrointestinal symptoms reported included constipation, diarrhea, nausea, vomiting, abdominal distension, and loss of appetite, while central nervous system symptoms may include headaches, insomnia, and drowsiness. Blood tests may show changes in white blood cell counts, elevated liver enzyme levels, and renal function abnormalities, requiring regular testing. Especially in cases where a malignant tumor is suspected, tests should be conducted before taking this drug, and if cancer is confirmed, discontinue use immediately. Elderly individuals may have weakened body functions, so when using this drug, dosage and dosing intervals should be adjusted, and they should be monitored closely. Patients undergoing dialysis may experience elevated drug concentrations in the blood, so it is essential to start with low doses and administer them cautiously. Pregnant women or women of childbearing age should only take this drug after consulting a physician if the benefits outweigh the risks, and nursing mothers are advised not to take this drug as it may be secreted in breast milk. Safety in pediatric patients has not been fully established, so caution should be exercised in its use. This drug should be kept out of the reach of children and stored in its original container; transferring to a different container may increase the risk of misuse or quality deterioration.

• Shock
• anaphylaxis symptoms
• facial pallor
• hypotension
• generalized rash
• dyspnea
• hepatic dysfunction
• jaundice
• agranulocytosis
• pharyngalgia

This drug should be stored in a tightly closed container to protect it from air and moisture, ideally at room temperature between 1 and 30 degrees Celsius. Storing it in this manner will help maintain the drug's efficacy for an extended period.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle