Aseranosemi Tablet

Adult dose

Children aged 12 and older and adults: The dosage is adjusted according to the patient's pain severity and treatment response. An initial dose of 4 tablets is recommended, and thereafter the dosing interval should be at least 6 hours, not exceeding 16 tablets in a day. The valid minimum dose should be administered for the shortest duration possible. Avoid unnecessary long-term use of this medication, and if long-term use is required due to the nature and severity of the disease, regular monitoring should be conducted to determine the need for continued use of this medication. Elderly Generally administer the adult dose. However, in elderly patients over 75 years, the half-life of tramadol has been increased by 17%, hence dosing should be provided with at least 6 hours interval. Renal Impairment For moderate renal impairment patients (creatinine clearance of 10-30 ml/min), dosing intervals should be extended to 12 hours. For severe renal impairment patients (creatinine clearance of less than 10 ml/min), it is not recommended to administer. Tramadol is removed very slowly during dialysis and filtration, so there is no need to re-administer this medication after dialysis for continued analgesic effect. Liver Impairment For moderate liver impairment patients, consider carefully extending the dosing interval. It is not recommended to administer to patients with severe liver impairment.

Child dose

The dosage is the same as for children aged 12 and older and adults.

This medicine should be consulted with a doctor or pharmacist before use for those who regularly consume more than three glasses of alcohol daily, as using this medication while drinking heavily can cause liver damage. During the use of this medicine, serious skin reactions like rashes or blistering may occur, and if such symptoms appear, it should be stopped immediately and a doctor should be notified. The components of this medicine may increase the risk of seizures, so patients with a history of seizures or those at high risk should exercise caution. Additionally, the risk of seizures may be increased when taken with certain antidepressants or other narcotic analgesics. For patients with severe asthma or respiratory difficulties, this medication can be life-threatening, so it must be taken in an environment where medical staff can monitor. Taking this medication with alcohol or central nervous system depressants may lead to severe drowsiness, respiratory depression, or coma, so it should be avoided or done under strict medical supervision. Those with head injuries or brain diseases should be cautious about the risk of increased intracranial pressure or respiratory depression when taking this medication. This medication can cause both psychological and physical dependence, so dosage and duration should be adjusted under doctor’s guidance if used long-term. Patients with impaired liver or kidney function must consult a doctor before taking this medication and be cautious not to exceed the recommended dosage. This medication should not be used in children under 12 years old or teenagers under 18 years old who have undergone tonsillectomy or adenoidectomy, and it is advisable to avoid its use in some adolescents aged between 12 and 18. This medication can cause drowsiness or dizziness, so driving or operating hazardous machinery should be avoided after taking it. In case of overdose, there is a risk of serious respiratory depression, seizures, liver damage, etc., so immediate medical treatment is required. Women who are pregnant or nursing must consult a doctor before taking this medication, particularly during breastfeeding, as it may pass into breast milk and affect the infant. While taking this medication, there may be drug interactions, so inform your doctor of all other medications being taken and observe carefully.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, abnormal respiratory symptoms accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headaches, seizures, confusion, vision changes, paralysis, urination.

Mild side effects

• Reduced appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a sealed container to prevent air entry and kept at a temperature between 1 and 30 degrees Celsius, which is safe to maintain its effectiveness over time.

Appearance

Pale yellow oblong film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle