Highple Naproxen Tablets (Naproxen Sodium)

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: Administer 275-550 mg of naproxen sodium per dose, twice daily (every 12 hours) orally. 2. Acute gout: Administer 825 mg orally as an initial dose, then 275 mg every 8 hours until the attack subsides. 3. Skeletal muscle disorders, post-surgical pain, pain after tooth extraction, dysmenorrhea, tendonitis, bursitis: Start with an initial dose of 550 mg orally.

This medication may cause gastric bleeding in individuals who regularly consume more than three alcoholic beverages per day, so consultation with a physician or pharmacist is essential. It may increase the risk of cardiovascular diseases such as myocardial infarction and stroke in individuals with heart or vascular problems or risk factors and should be monitored closely. Elderly patients should be particularly cautious as there may be a risk of severe issues such as ulcers or bleeding in the stomach or intestines; they must consult a physician immediately if any unusual symptoms occur during administration. This medication should not be taken by individuals with peptic ulcers, severe blood disorders, significant liver or kidney dysfunction, severe hypertension, or allergies to this medication or NSAIDs. Those with a history of peptic ulcers or blood disorders or issues with kidney, liver, or heart function should use this medication cautiously and may require regular testing. In case of respiratory distress, hives, skin rashes, severe abdominal pain, bleeding, or symptoms of liver or kidney dysfunction occur, use should be stopped immediately and a physician consulted. This medication should not be taken in conjunction with other NSAIDs to reduce the risk of side effects. It should also be avoided during late pregnancy as it may harm the fetus, and breastfeeding individuals should refrain from using it to prevent transmission to breast milk, which could affect the infant. Safety has not been established for children under 2 years, so it is preferable not to administer it to them. Older adults should start with a lower dose and monitor for adverse reactions.

Serious side effects

• Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions
• Severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, severe skin reactions
• Shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever
• Yellowing of the skin or eyes, extreme lethargy, liver issues (jaundice)
• Sudden and severe headaches, thunderclap headaches, fainting

Mild side effects

• Gastric discomfort
• abdominal pain
• nausea
• vomiting
• loss of appetite
• indigestion
• heartburn
• diarrhea
• constipation
• stomatitis

Drug interactions

Do not take this medication with other NSAIDs, naproxen derivatives, aspirin, or high doses of methotrexate. Avoid concurrent use with hydantoins, sulfonamides, sulfonylureas, propranolol and other beta-blockers, ACE inhibitors, loop diuretics, thiazide diuretics, probenecid, lithium, low-dose methotrexate, coumarin anticoagulants, zidovudine, and fluoroquinolone antibiotics.

This medication should be stored in a tightly sealed container to protect it from air and moisture, at a safe temperature between 1 degrees Celsius and 30 degrees Celsius. Storing it this way will help maintain its efficacy for a longer period.

Appearance

Pale blue round film-coated tablet

Package unit

Box - 10 tablets/box [10 tablets/PTP], Box - 480 tablets/box [120 pouches (2 tablets/pouch) × 2], Box - 960 tablets/box [2 tablets/pouch × 480], Bottle - 1000 tablets/bottle