Medication info

Moperin M Tablets (Domperidone Maleate)

Prescription medicationExpired
Ingredient · strength
Domperidone Maleate›Strength being verified
Manufacturer / importer
Mothers Pharmaceutical Co., Ltd.
Appearance
White round tablets
Packaging
1000 tablets/bottle
Approval status
Expired

MFDS item code 201308625 · Approved 2013.07.31

This product's status changed to Expired on 2023.07.31. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Relief of gastrointestinal symptoms (nausea and vomiting)
Who uses it
Adults · Children
Adult dosage
In general, do not use for more than 1 week.
Children's dosage
Adults and adolescents (12 years and older, 35kg or more): Administer 10mg (5mg when levodopa is administered) of domperidone orally 3 times daily before meals. The maximum daily dose is 30mg.

Ingredients

Manufacturer
Mothers Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of gastrointestinal symptoms (nausea and vomiting)

  • Symptoms of nausea and vomiting
View approved original text

This medication is used to relieve symptoms of nausea and vomiting.

Dosage and Administration

Adult dosage

In general, do not use for more than 1 week.

Children's dosage

Adults and adolescents (12 years and older, 35kg or more): Administer 10mg (5mg when levodopa is administered) of domperidone orally 3 times daily before meals. The maximum daily dose is 30mg.

Precautions

This medication should not be used in certain patients. Patients who are allergic to this medication or have experienced hypersensitivity reactions should not take it. This medication may be dangerous for patients with gastrointestinal bleeding, mechanical intestinal obstruction, or perforation as it promotes gastrointestinal motility. Patients with prolactin-secreting tumors should avoid this medication as it can enhance prolactin secretion. Patients taking strong CYP3A4 inhibitors or those taking medications that prolong the QTc interval should also refrain from using this medication. It is not administered to patients with moderate to severe liver impairment and to pregnant women or those who may become pregnant. It can be risky for patients with prolonged cardiac conduction intervals or heart diseases such as electrolyte imbalance or heart failure. Furthermore, patients with lactose intolerance or certain genetic metabolic disorders should exercise caution. The use of this medication is not appropriate for children, especially those weighing less than 35 kg, and infants under 1 year old require particular caution. Patients with impaired renal or liver function and elderly patients may experience stronger side effects, so it should be administered carefully. Patients with a history of heart disease also need to take caution when using this medication. This medication may cause side effects such as dry mouth, drowsiness, headaches, diarrhea, rashes, itching, and excessive milk secretion. Rarely, serious side effects such as anaphylaxis, dizziness, seizures, cardiac arrhythmias, breast pain, and weakness have also been reported. Particularly, high doses or prolonged use may lead to increased prolactin-related adverse reactions. Since it is primarily metabolized in the liver, caution is needed in patients with liver damage, and patients with severe renal failure should have their dosages and frequency reduced. Patients with a history of breast cancer should use this medication carefully, as prolactin secretion may be affected. Drowsiness or dizziness may occur after taking this medication, so it is advisable to avoid driving or operating machinery. This medication may interact with various drugs, so if you are taking other medications, be sure to consult your doctor or pharmacist. It can be risky to take it with medications that prolong cardiac conduction intervals or strong CYP3A4 inhibitors. It is safer for pregnant or breastfeeding women not to take this medication, and care should be taken as side effects may occur in newborns while breastfeeding. In the case of overdose, symptoms such as anxiety, confusion, seizures, and Parkinsonian symptoms may appear, so it is important to visit a medical institution immediately, and appropriate treatment such as ECG monitoring may be necessary. This medication should be stored out of reach of children, and kept in the original container to prevent misuse or degradation of quality.

Side effects

  • Dyspepsia
  • gastroesophageal reflux disease
  • irritable bowel syndrome
  • nausea
  • vomiting
  • dry mouth
  • loss of libido
  • anxiety
  • drowsiness
  • headache
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  • diarrhea
  • rash
  • itching
  • galactorrhea
  • breast pain
  • breast tenderness
  • weakness
  • restlessness
  • nipple discharge
  • breast enlargement
  • breast swelling
  • depression
  • hypersensitivity
  • lactation disorder
  • irregular menstruation
  • anaphylactic reaction
  • agitation
  • irritability
  • dizziness
  • extrapyramidal disorder
  • convulsions
  • ocular motility seizure
  • ventricular arrhythmia
  • acute cardiac death
  • Torsades de Pointes
  • QTc prolongation
  • vascular edema
  • hives
  • urinary retention
  • gynecomastia
  • amenorrhea
  • abnormal liver function tests
  • increased serum prolactin
  • edema
  • confusion
  • altered consciousness
  • spatial disorientation
  • Parkinson's syndrome

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container that is not exposed to air, and it is best to store it at room temperature between 1 and 30 degrees Celsius. Storing it this way can maintain the effectiveness of the medication and prevent degradation.

Appearance and packaging

Appearance

White round tablets

Package unit

1000 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.