BM Heparin Sodium Injection 20000 Units

Adult administration

Typically administered intravenously or added to circulating blood during extracorporeal circulation. 1. Extracorporeal Circulation 1) Artificial Kidney (1) Systemic Heparinization: Administer heparin sodium 1,000 to 5,000 IU before starting dialysis, and after dialysis starts, continuously administer 500 to 1,500 IU per hour or intermittently add 500 to 1,500 IU every hour. (2) Local Heparinization:

This medication is very powerful, so it must be used only under the strict supervision of a physician. Patients with diseases that have a high risk of bleeding should use this medication with caution, as bleeding can occur in almost any part of the body for patients who have received this drug. The benzyl alcohol component contained in this medication can cause life-threatening respiratory problems in premature infants or newborns, so it should not be used in these patients. It should not be administered to patients who have had an allergic reaction to this medication or its components, whose blood coagulation tests have been outside normal ranges, or those with bleeding or a tendency to bleed. Patients with severe liver or kidney disease, those who have recently had surgery on the central nervous system or eyes, and patients who have received spinal or epidural anesthesia should also be evaluated carefully before using this medication. Patients with consumptive coagulopathy, pregnant women in their late stages, children or older adults, and individuals with alcohol dependence should have their blood coagulation status periodically checked and observed closely when using this drug. This medication can cause various side effects such as bleeding, thrombocytopenia, liver function abnormalities, allergic reactions, skin issues, and local pain, so any unusual symptoms should be reported to medical personnel immediately. Blood coagulation tests should be conducted to adjust the dosage of this medication, and if bleeding worsens or there is a significant drop in platelet numbers, administration should be stopped. Thrombocytopenia caused by this medication can be associated with serious thrombosis, so regular platelet count tests and careful monitoring are necessary. This drug can interact with various other medications, so if you are taking other medications, be sure to inform your doctor or pharmacist. Women who are pregnant or breastfeeding should use this medication with increased caution due to the risk of bleeding in the fetus and newborn, and because the benzyl alcohol component can pass through the placenta and into breast milk. Safety in children has not been adequately established, so special caution is required when administering it to children. Older adults have a higher risk of bleeding, so they should be observed more carefully when using this medication. In case of overdose, severe bleeding may occur, so notify medical personnel immediately, and if necessary, administer the antidote protamine sulfate to neutralize this medication. Intramuscular injections should be avoided due to the risk of bruising, and it should not be mixed with antihistamines for injection.

Serious side effects

Hives, severe swelling (angioedema), chest tightness (pressure sensation), difficulty breathing, hypotension, shock (severe allergic reaction), severe rash with high fever, skin peeling (hemorrhagic necrosis), dyspnea, bronchial asthma, asthma attacks, cyanosis, severe skin reactions, thrombocytopenia, heparin-induced thrombocytopenia (HIT), thrombosis, liver abnormalities (elevations in γ-GTP, LDH, AST, ALT), liver

Mild side effects

• Itching
• chills
• fever
• rhinitis
• tearing
• conjunctivitis
• tachycardia
• pressure sensation
• nausea
• vomiting

This medication is sensitive to light, so it should be stored in a tightly sealed container that does not allow light to enter. Additionally, it is important to maintain the storage temperature between 1 degree and 30 degrees Celsius room temperature. Proper storage will help maintain the effectiveness of the medication and prevent deterioration.

Appearance

A clear liquid that is colorless or pale yellow contained in a brown vial

Package unit

20mL/vial X 10 vials