Medication info
Youngil Clarithromycin Tablet 250mg

Youngil Clarithromycin Tablet 250mg

Prescription medicationTabletOral
Ingredient · strength
Clarithromycin›250mg / 1 tablet
Manufacturer / importer
Youngil Pharmaceutical Co., Ltd.
Appearance
Yellow oval film-coated tablet with a vanilla flavor
Packaging
30 tablets/bottle, 200 tablets/bottle
Approval status
Active

MFDS item code 201307946 · Approved 2013.06.28 · Insurance code 649404570

Summary

Main use
Treatment of respiratory and skin infections, mycobacterial infections, and Helicobacter pylori eradication
Who takes it
Adults · Children
Adult dose
○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7~14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days in these patients. ○ Mycobacterial infections: Administer 500mg (potency) twice daily. In this case, it must be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer this drug 500mg (potency) three times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for an additional 14 days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1~14) and omeprazole 40mg once daily for 28 days (days 1~28).
Child dose
○ Children aged 12 years and older: Same as adults ○ For children under 12 years of age, use clarithromycin dry syrup.

Ingredients

Manufacturer
Youngil Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of respiratory and skin infections, mycobacterial infections, and Helicobacter pylori eradication

  • Bronchitis
  • pneumonia
  • pharyngitis
  • sinusitis
  • skin and skin tissue infections
  • mycobacterial infections
  • duodenal ulcers
View approved original text

This medication is used to treat infections caused by various bacteria. It is effective in lower respiratory tract infections such as bronchitis and pneumonia, upper respiratory tract infections such as pharyngitis and sinusitis, as well as skin and skin tissue infections. Additionally, it is used to treat mycobacterial infections caused by Mycobacterium avium and Mycobacterium intracellularis and to eradicate Helicobacter pylori which causes duodenal ulcers. It covers various strains to improve several symptoms caused by bacterial infections. This medication plays a crucial role in helping patients treat infections, so it can be taken with confidence.

How to take

Adult dose

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7~14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days in these patients. ○ Mycobacterial infections: Administer 500mg (potency) twice daily. In this case, it must be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer this drug 500mg (potency) three times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for an additional 14 days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1~14) and omeprazole 40mg once daily for 28 days (days 1~28).

Child dose

○ Children aged 12 years and older: Same as adults ○ For children under 12 years of age, use clarithromycin dry syrup.

Precautions

This medication should not be used in patients with certain medications or conditions. For example, patients who have had allergic reactions to this medication or who have had hypersensitivity to certain antibiotics should not take it. Also, patients with heart rhythm abnormalities or severe liver or kidney dysfunction should not take this medication. Women who are pregnant or nursing should not use this medication, and children or patients with certain genetic diseases should also exercise caution. This medication should be administered cautiously to patients with weakened liver or kidney function, the elderly, or patients with heart diseases. In cases where other antibiotics or multiple medications are being taken simultaneously, interactions may occur, so caution should be exercised. During the course of this medication, it is important to closely monitor for any allergic symptoms or serious side effects. If symptoms such as difficulty breathing, rashes, severe abdominal pain, diarrhea, hearing abnormalities, or changes in mental status occur, immediately discontinue use and consult medical personnel. This medication may cause various side effects such as gastrointestinal disturbances, liver dysfunction, kidney function decline, blood abnormalities, and central nervous system symptoms that may require regular examinations. Moreover, this medication has a high potential for interactions with other drugs, particularly when taken with drugs affecting the heart or those metabolized by the liver, extra caution is warranted. It is safest for pregnant and nursing women not to take this medication, and if necessary, they must consult with medical personnel before taking it. The safety and efficacy of this medication have not been adequately established for children, so it is not recommended for children under 12 years of age. Elderly patients may require dosage adjustments due to potential kidney function decline. In cases of overdose, gastrointestinal disturbances or psychological symptoms may occur, hence strict adherence to dosage is essential. This medication should not be stored in a refrigerator, should be kept away from direct sunlight, and stored at room temperature.

Side effects

Shock, anaphylactic symptoms, difficulty breathing, seizures, flushing, rash, itching, hives, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, indigestion, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, loss of appetite, constipation, stool discoloration, colitis due to a membrane, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, seizures, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, increased CPK, elevated serum myoglobin, elevated urinary myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, gustatory dysfunction, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbance, hypoglycemia, tinnitus, auditory impairment, purpuric rash, acute generalized pustular psoriasis, muscle cramps, musculoskeletal rigidity, myopathy, elevated blood urea, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased International Normalized Ratio, prolonged prothrombin time, abnormal urine color, asthma, nosebleeds, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, bullous dermatitis, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura

Not everyone experiences these, and they can vary from person to person.

Storage

This medication can be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is best to keep the storage temperature between 1 degree and 30 degrees Celsius at room temperature. This helps maintain the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

Yellow oval film-coated tablet with a vanilla flavor

Package unit

30 tablets/bottle, 200 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.