Olpat 20 mg (Atorvastatin Calcium Trihydrate)

Adult dose

For the treatment of hyperlipidemia, the recommended initial dose is 10 mg once daily, and if a greater reduction in LDL cholesterol is needed, it can be initiated at 20 mg or 40 mg once daily. Doses are administered within a range of 10–80 mg once daily. The dose should be individualized based on patient characteristics, and lipid levels should be analyzed within 2-4 weeks after initiation or dose adjustment to modify the dose according to responses. The treatment goal is to lower LDL cholesterol levels, so it is recommended to use LDL cholesterol levels for evaluation during treatment initiation and response assessment. However, if LDL cholesterol levels are not available, total cholesterol levels should be used to monitor treatment response. In patients with homozygous familial hypercholesterolemia, the administration range is 10–80 mg once daily, used in conjunction with other lipid-lowering therapies (e.g., LDL apheresis) or when such methods are not feasible. For pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia, the recommended initial dose is 10 mg once daily, and the recommended maximum dose is 20 mg once daily (there is no clinical data on dosages greater than 20 mg in this age group). The dosage should be adjusted appropriately according to therapeutic goals for individual patients at an interval of 4 weeks or more. ○ In patients with renal impairment: Kidney disease does not affect the plasma concentration of atorvastatin or its LDL cholesterol-lowering effects, so dosage adjustment is not necessary. ○ In the elderly: The effectiveness and safety of this drug in patients aged 70 and older are similar to those in the general adult population.

Child dose

The recommended initial dose for pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia is 10 mg once daily, and the maximum dose is 20 mg once daily. The dosage should be adjusted according to the therapeutic goals at intervals of at least 4 weeks.

This medication may cause muscle problems, so use should be stopped immediately if muscle pain or weakness occurs, or if muscle-related values are elevated in blood tests. This medication may affect liver function, so patients with liver disease or abnormally high liver enzyme levels should not take it. Women who are pregnant, may become pregnant, or are breastfeeding should not take this medication. This medication should not be given to children under 10 years of age or those with certain genetic disorders. Patients with a history of alcohol abuse or liver disease, as well as those with impaired kidney function, should use this medication with caution and require regular monitoring. This medication may interact with other drugs, so it is essential to consult a doctor or pharmacist, especially when taking certain antibiotics, antifungals, or antivirals. Side effects such as muscle pain, cramps, weakness, insomnia, digestive disorders, headache, rash, etc. may occur, and if any unusual symptoms arise, medical personnel should be informed immediately. While taking this medication, regular blood tests and liver function tests should be performed, and if any abnormal findings appear, discontinuation of the medication should occur. There is no specific antidote for overdose, so treatment and examination according to symptoms are necessary. Keep this medication out of the reach of children and store it in its original container. Proper contraceptive methods should be utilized while taking this medication, and if pregnancy is confirmed, use should be discontinued immediately.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/visual mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), severe lethargy, liver issues (jaundice), sudden and very severe headache, thunderclap headache, pain

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius to ensure the medication's effectiveness.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle