TGP Simvastatin 20 mg

Adult dose

The dosage for adults is 5 to 40 mg once daily in the evening. The initial starting dose of Simvastatin is 40 mg per day, with a common initial starting dose being 20 mg, and for patients with mild to moderate hypercholesterolemia, it can begin at 10 mg. Certain patient groups may have different dosages; for example, the elderly should start with 20 mg per day, while those taking verapamil or diltiazem or dronedarone should start with 10 mg per day.

Child dose

The recommended initial dose for pediatric patients (aged 10 to 17 years) with heterozygous familial hypercholesterolemia is to take 10 mg once daily in the evening, with a recommended dosage range of 10 to 40 mg per day, and the recommended maximum dose is 40 mg per day.

This medication requires caution as it may cause muscle problems. Especially at high doses, there is an increased risk of muscle damage known as myopathy or rhabdomyolysis. Patients who are allergic to this medication or have impaired liver function, as well as pregnant or nursing women, should not use it. Additionally, it can be dangerous when taken with certain strong medications, so consultation with a physician is necessary. Individuals who consume excessive amounts of alcohol or have liver or kidney problems, those with hypothyroidism or a history of muscle disorders, elderly individuals, and women should be particularly cautious when using this medication. If symptoms such as muscle pain, muscle weakness, or pain occur while taking this medication, it is essential to notify a physician immediately, and sometimes it may be necessary to discontinue the medication. Regular liver function tests are important as liver function abnormalities may occur. If symptoms of hepatitis or jaundice appear, notify a physician immediately. This medication may interact with other drugs, so if you are taking other medications, be sure to inform healthcare providers, particularly when used with certain antibiotics, antifungals, immunosuppressants, calcium channel blockers, etc., dosage adjustment or discontinuation may be necessary. Women who are planning to become pregnant or are potentially pregnant should use contraception and must discontinue the medication immediately if pregnancy is confirmed. Use in children aged 10 years and older, especially between the ages of 10 and 17, should be limited, and consultation with healthcare providers regarding effects on growth and maturation is necessary. Elderly patients may respond differently to the medication, so caution is required during use. In case of overdose, seek immediate medical attention for appropriate treatment. This medication must be stored out of reach of children, and it should be kept in its original container to maintain its quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in mouth/eye mucous membranes, shortness of breath or difficulty breathing, asthma attack, respiratory issues with coughing+fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, impaired vision, paralysis, urination

Mild side effects

• Abdominal pain
• fatigue
• constipation
• diarrhea
• indigestion
• bloating
• nausea
• headache
• upper respiratory infection
• edema

This medication should be stored in a tightly closed container to prevent the ingress of air or moisture. It is advisable to maintain a storage temperature between 1 degree and 30 degrees Celsius. Proper storage will help keep the medication effective for a longer period.

Appearance

Yellowish-brown oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle