Isilin Duo Dry Syrup (Amoxicillin, Potassium Clavulanate (7:1))

Adult dosage

In mild to moderate infections such as recurrent tonsillitis, upper and lower respiratory tract infections, urinary tract infections, and skin/soft tissue infections, 25 mg/3.6 mg per kg of body weight is usually taken twice a day. In severe infections such as acute otitis media, sinusitis, acute bronchopneumonia, and urinary tract infections, 45 mg/6.4 mg per kg of body weight is usually taken twice a day. To minimize the potential for gastrointestinal intolerance,

Children's dosage

The 7:1 syrup is not suitable for children under 2 months and pediatric patients with renal impairment. The administration method is based on dosage per kg of weight, given at the start of meals.

This drug is a β-lactam antibiotic and should not be administered to certain patients. For example, it should not be used in patients who have had allergic reactions to this drug's components or to penicillin drugs. It is also contraindicated in patients with viral infections such as infectious mononucleosis or lymphocytic leukemia due to the increased risk of rash. Patients with a history of liver dysfunction or jaundice may experience a recurrence of symptoms if this drug is used. Patients with impaired liver function or severe kidney disease may have increased drug concentrations, so dosage and administration intervals should be adjusted. Caution is required for patients with allergic diathesis, difficulty in oral ingestion, the elderly, or those in poor general condition, as they may have a risk of side effects such as vitamin K deficiency. Patients with gastrointestinal diseases such as vomiting or diarrhea may not absorb the medication sufficiently. While taking this medication, gastrointestinal symptoms may appear such as diarrhea, vomiting, and abdominal pain, and in rare cases, severe colitis may occur, so use should be discontinued immediately if symptoms are severe. Regular liver function checks should be conducted during long-term use as abnormal liver function tests or jaundice symptoms may develop. Rarely, serious allergic reactions such as rash, itching, or Stevens-Johnson syndrome may occur, so if a rash develops, a physician should be consulted immediately. Blood tests have reported reactions such as leukopenia, anemia, and thrombocytopenia. Neurological abnormalities may rarely occur, including dizziness, headaches, and seizures. Kidney function may suddenly worsen; therefore, kidney function should be monitored regularly and drug use should be discontinued if abnormalities arise. This medication can interact with other drugs, particularly anticoagulants, certain antibiotics, anti-inflammatory drugs, and oral contraceptives, so caution is necessary when taken together. Women in early pregnancy or breastfeeding should consult a doctor before using this medication, and nursing mothers should observe their infants for potential side effects. The safety of this medication in children, especially newborns or premature infants under 2 months old, has not been established; therefore, caution should be exercised. Elderly patients are at a higher risk of side effects due to decreased bodily function, making dosage adjustment and status monitoring important. Regular liver function, kidney function, and blood tests should be performed while taking this medication, and in cases of overdose, gastrointestinal symptoms or neurological abnormalities may occur, requiring immediate contact with a medical institution. The medication should be stored in a closed container after preparation, and it is recommended to finish taking it within 7 days. Additionally, the medication should be well shaken before use, and unnecessary long-term use should be avoided.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory disorders accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme fatigue, sudden and severe headache, lightning-like headache, seizures, confusion, visual disturbances, paralysis, urinary changes

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• nausea
• vomiting
• loss of appetite
• abdominal pain

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. Furthermore, it is important to store it in a dry place below 25 degrees Celsius to maintain its efficacy.

Appearance

A whitish powder with a peculiar smell for preparing syrup by dissolving in water.

Package unit

50ml/bottle*10