Glipion Tablets (Glimepiride)

Adult dose

Adjust individually for each patient. Swallow without chewing with more than 1/2 cup of water. This medication is taken orally once daily before breakfast or right before the first meal. For monotherapy, in patients who have not previously received medication, treatment begins with 1 mg once daily and may be increased by 1 mg at intervals of 1 to 2 weeks. Generally, additional effects are minimal beyond 4 mg.

This medication should not be administered to patients with insulin-dependent diabetes or those in a state of diabetic ketoacidosis or coma. Patients with hypersensitivity to this medication or to sulfonylureas, sulfonamides should also not use it. It is also unsafe for individuals with severe liver or kidney damage, as well as pregnant or breastfeeding women. Patients with severe infections, before and after surgery, or with severe trauma are recommended to transition to insulin therapy. Patients with gastrointestinal disorders may be at risk of hypoglycemia due to improper food absorption, requiring caution. During initial dosing, the risk of hypoglycemia is high; therefore, blood sugar changes must be carefully monitored, especially in elderly patients or those with irregular meals or poor nutritional status. Alcohol consumers or individuals with diminished liver or kidney function may also have increased risk of hypoglycemia. This medication lowers blood sugar levels and may elicit hypoglycemic symptoms, which can include headaches, severe hunger, nausea, fatigue, confusion, drowsiness, and loss of consciousness, among other symptoms. In the event of hypoglycemia, consuming sugar-containing foods to quickly raise blood sugar levels is crucial. During treatment with this medication, liver abnormalities, blood abnormalities, and allergic reactions may occur, warranting immediate consultation with a doctor if any unusual symptoms arise. This medication should be taken regularly along with a proper diet and exercise program, and continuous monitoring of blood sugar levels is necessary. If taken with other medications, interactions may impact blood sugar control, so patients must inform their physician or pharmacist about any concurrent medications. Pregnant or breastfeeding women should not use this medication and should transition to insulin therapy if necessary. Safety in patients under 18 years has not been established, and dosage adjustments may be necessary for the elderly considering kidney function. In cases of overdose, severe hypoglycemia may occur, requiring immediate medical treatment, and the medication should be stored out of reach of children.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions, hypotension, shock, serious allergic reactions, thrombocytopenia, severe thrombocytopenia with thrombocytopenic purpura, Stevens-Johnson syndrome, liver dysfunction (cholestasis, jaundice), hepatitis, hemolytic anemia, leukopenia, agranulocytosis, pancytopenia, serious blood disorders, severe hypoglycemia (loss of consciousness and coma, seizures), stroke

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• reduced motivation

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, preferably at room temperature between 1 and 30 degrees Celsius. By doing so, the efficacy of the medication can be preserved for a longer time.

Appearance

Green, oblong tablet

Package unit

30 tablets/bottle, 300 tablets/bottle