Dear Medi Tablet 4 mg (Glimpiride)

Adult dose

This medication is administered orally once daily. It should be taken before breakfast or immediately before the first meal. The initial dose is 1 mg of Glimpiride taken once daily. If necessary, the dose may be increased by 1 mg at intervals of 1 to 2 weeks. Generally, doses exceeding 4 mg show minimal additional efficacy, but in some cases, increases to 6 mg or 8 mg may be possible. If 4 mg daily fails, consider switching to insulin.

This medication should not be used in patients with insulin-dependent diabetes, diabetic ketoacidosis, or those in a coma. Additionally, patients who have had allergic reactions to this medication, sulfonylureas, or sulfonamides should not take it. There is no experience in usage for patients with severe liver or kidney impairment, thus switching to insulin therapy is recommended. Pregnant women, women who may become pregnant, and nursing mothers should not take this medication. Patients with severe infections, surgery, or serious trauma should also be treated with insulin. When gastrointestinal disorders such as diarrhea or vomiting occur, absorption of medication may be reduced, increasing the risk of hypoglycemia, so caution is needed. During the first week of taking this medication, there is a high risk of hypoglycemia, so blood sugar should be checked frequently and closely monitored. Particularly, older adults, patients with poor nutritional status or irregular eating patterns, those with mismatched exercise and carbohydrate intake, changes in meal patterns, or those who frequently consume alcohol should be extra cautious. Patients with weak kidney or liver function, those who overdose on this medication, or those with thyroid or adrenal dysfunction are also at higher risk for hypoglycemia and should be careful. Moreover, when taking with other medications, interactions can affect blood sugar control, so it is essential to inform doctors or pharmacists. The most common side effect while taking this medication is hypoglycemia, which may present as headache, severe hunger, nausea, fatigue, anxiety, confusion, drowsiness, or decreased consciousness. If symptoms of hypoglycemia occur, sugar should be taken immediately, and if symptoms are severe, medical assistance should be sought. Additionally, temporary blurred vision, nausea, vomiting, and abdominal pain may occur as gastrointestinal symptoms. Serious side effects such as liver dysfunction or decreased blood cell counts may rarely occur; consult a doctor immediately if abnormal symptoms arise. Allergic reactions such as skin rash, hives, or difficulty breathing may occur, and if these symptoms appear, discontinue the medication and visit a healthcare facility immediately. When taking this medication, regular meals, exercise, and weight management are crucial, and blood sugar control status should be monitored continuously. If hypoglycemia occurs, quickly raise blood sugar by consuming sugar or sugary drinks; artificial sweeteners will not be effective. In special circumstances such as stress, injury, surgery, or infection, blood sugar control may become difficult, and temporary switching to insulin therapy may be necessary. If other diseases arise or lifestyle changes occur while taking this medication, consult a doctor to adjust dosage or administration method. This medication is excreted through the kidneys, so elderly patients or those with impaired kidney function should be especially cautious regarding dosage adjustments. In the event of overdose, severe hypoglycemia may occur, requiring immediate emergency measures, which may include inducing vomiting, gastric lavage, or glucose injection. The safety and efficacy of this medication have not been established for children, so it should not be used in individuals under 18 years of age. Pregnant or nursing women should not take this medication, and switching to insulin therapy is advisable if necessary. When storing this medication, keep it out of reach of children and store it sealed in the original container. Finally, when taking this medication alongside other medications or discontinuing them, it may affect blood sugar control, so it is crucial to inform healthcare professionals and follow their instructions.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, serious allergic reactions accompanied by hypotension, Stevens-Johnson syndrome, anaphylaxis, angioedema, liver dysfunction (jaundice), severe liver failure, serious blood changes (thrombocytopenia, leukopenia, hemolytic anemia, anemia, agranulocytosis, pancytopenia, aplastic anemia), accompanied by thrombocytopenic purpura.

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggressiveness
• decreased concentration
• decreased agility or activity

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is important to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature. This storage method helps safely maintain the medication's efficacy.

Appearance

Light blue rectangular tablets

Package unit

30 tablets/bottle, 300 tablets/bottle