Naxen Soft Capsules (Naproxen)

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: Take 250–500 mg (1–2 tablets) of Naproxen orally, twice a day (every 12 hours). 2. Acute gout: Take a loading dose of 750 mg (3 tablets), and then take 250 mg (1 tablet) orally every 8 hours until the attack subsides. 3. Skeletal muscle disorders, postoperative pain, pain after tooth extraction, dysmenorrhea, tendonitis, bursitis: Take a loading dose of 500 mg of Naproxen orally.

Patients who regularly consume more than three drinks a day must consult with a physician or pharmacist before taking this medication. Regular drinkers of alcohol may have an increased risk of gastric bleeding while on this medication. This drug may have effects on the cardiovascular system, so patients with a history of heart disease or vascular issues should take special care. If cardiovascular symptoms appear, they must inform medical personnel immediately, regardless of whether they have a history of cardiovascular diseases. This medication may cause gastrointestinal burden, and serious issues such as gastric bleeding, ulcers, or perforations may occur, so patients must pay attention to gastric symptoms while taking it. Especially, elderly patients or those with a history of gastrointestinal disorders are at greater risk with this medication, requiring careful observation. Patients with peptic ulcers, severe blood disorders, liver impairment, very weak cardiac function, severely decreased renal function, and severe hypertension should not take this medication. Patients allergic to this drug or non-steroidal anti-inflammatory pain relievers, or have a history of hypersensitivity such as asthma, rhinitis, or urticaria, should avoid taking it. This medication may harm the fetus in the later stages of pregnancy, so it should not be used during that time. Nursing mothers are advised against using this medication as it may transfer to breast milk and cause side effects in infants. It is preferable not to use this medication in children under 2 years of age as its safety has not been established. Elderly patients have a higher risk of side effects such as gastric bleeding when taking this medication, so it should be used cautiously at the minimum dosage. When taking this medication for an extended time, periodic blood tests, liver function tests, and kidney function tests should be performed to monitor for abnormalities. Co-administration with other non-steroidal anti-inflammatory drugs may increase the risk of side effects, so such combinations should be avoided. When co-administering with specific drugs, interactions may occur, so consultation with a physician or pharmacist is necessary before taking. If severe headaches, rashes, difficulty breathing, signs of gastric bleeding, jaundice, or symptoms indicating decreased renal function occur during use, the medication should be discontinued immediately and medical consultation sought. Overdose may lead to symptoms such as drowsiness, nausea, and vomiting, necessitating immediate emergency treatment. This medication should be stored out of reach of children and care should be taken not to transfer it to another container, as this may alter its quality.

Serious side effects

Urticaria, severe swelling (edema), cold sweats, difficulty in breathing, respiratory distress, asthma episodes, hematemesis, gastric bleeding, peptic ulcers, perforation, blood disorders (agranulocytosis, leukopenia, thrombocytopenia, etc.), jaundice, hepatitis, renal impairment, hematuria, hyperkalemia, interstitial nephritis, nephrotic syndrome, renal failure, aseptic meningitis, severe headaches, confusion, Stevens-Johnson syndrome, epidermal necrolysis, anaphylactic reaction, eosinophilia, and

Mild side effects

• Nausea
• stomach pain
• abdominal pain
• vomiting
• loss of appetite
• dyspepsia
• heartburn
• diarrhea
• constipation
• stomatitis

Drug interactions

Do not take this medication with other non-steroidal anti-inflammatory drugs and Naproxen derivatives. Phenytoin-type anticonvulsants, sulfonamides, sulfonylurea blood glucose-lowering agents, propranolol and other beta-blockers, ACE inhibitors (such as captopril), loop diuretics and thiazide diuretics, probenecid, aspirin, lithium, methotrexate, coumarin anticoagulants (such as warfarin), zidovudine, fluoroquinolone antibiotics (such as enoxacin)

This medication should be stored in a tightly closed container to protect it from air and moisture. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius.

Appearance

Green translucent oblong soft capsule containing light yellow to pale green contents

Package unit

10 capsules (10 capsules/PTP x 1)