Stavorin Tablets (Thienyl Sodium)

Adult dose

○ Adults: Administer 12.5 mg of tianeptine sodium orally 3 times daily before meals. ○ In patients 70 years of age or older or patients with renal failure, limit administration to 2 times daily. ○ The dose may be adjusted as appropriate according to symptoms. ○ Abrupt discontinuation of treatment should be avoided. The dose should be gradually reduced over 7 ~ 14 days to reduce the risk of withdrawal reactions. (See the “General precautions” section under Precautions for Use.)

This medication is used to treat depression, and during treatment, there may be an increased risk of suicidal thoughts or self-harm behaviors, particularly during the initial phase of treatment and when changing doses, so patients should be closely monitored. This medication should not be administered to children under 15 years of age, patients with certain genetic disorders, or patients taking MAO inhibitors. Common side effects during use may include appetite loss, insomnia, drowsiness, headaches, palpitations, gastrointestinal disturbances, and muscle pain, while rarely, psychiatric symptoms such as suicidal thoughts, confusion, and hallucinations may occur. Before surgery, patients should inform the anesthesiologist that they are taking this medication and may need to discontinue it 24 to 48 hours prior to surgery if necessary. It is advisable not to take this medication with alcohol or drugs containing alcohol, and caution is required for patients with drug dependence or a history of substance abuse. Do not abruptly discontinue use; instead, gradually reduce the dosage as directed by a physician. Patients should be cautious when driving or operating machinery due to the possibility of drowsiness. Patients with impaired renal function or those over 70 years of age should adjust the dosing amount and frequency, and careful monitoring is necessary as electrolyte imbalances such as hyponatremia may occur. In case of overdose, seek medical assistance immediately for appropriate treatment; while there is no specific antidote, symptomatic treatment and monitoring are required. Keep this medication out of the reach of children, and store it in its original container to maintain quality.

• Loss of appetite
• hyponatremia
• nightmares
• drug abuse and dependence
• suicidal thoughts
• suicidal behavior
• confusion
• hallucinations
• insomnia
• drowsiness

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The recommended storage temperature is room temperature between 1 and 30 degrees Celsius.

Appearance

White oval film-coated tablet

Package unit

30 tablets per bottle, 300 tablets per bottle