Jekona Tablet 100 mg (Itraconazole Solid Dispersion)

Adult dose

To improve absorption, this medicine should preferably be taken immediately after meals. 1. Short-term treatment 1) Candidal vaginitis: Administer itraconazole 200 mg per dose twice daily (morning and evening) for 1 day, or 200 mg once daily for 3 days. 2) Tinea versicolor: Administer 200 mg once daily for 7 days. 3) Tinea corporis and tinea cruris (jock itch): Administer 100 mg once daily for 15 days. 4) Tinea manuum (interdigital type) and tinea pedis (interdigital type): Administer 100 mg once daily for 15 days. 5) Tinea manuum (palms) and tinea pedis (soles): Administer 100 mg once daily for 30 days or 200 mg per dose twice daily for 7 days. 6) Oral candidiasis: Administer 100 mg once daily for 15 days. 7) Fungal keratitis: Administer 200 mg once daily for 21 days. 2. Onychomycosis 1) Pulse therapy Administer 200 mg per dose twice daily for 1 week, followed by 3 weeks without treatment; this constitutes one cycle. Administer up to 2 cycles for infection limited to fingernails and up to 3 cycles for infection of the toenails. 2) Continuous therapy Administer 200 mg once daily for 3 months. The therapeutic effect continues for 3 months for fingernails and 6 months for toenails after treatment ends. 3. Systemic fungal infections In patients with reduced immune function, such as those with neutropenia, AIDS, or an organ transplant, the oral bioavailability of this medicine may be reduced; if necessary, increase the dose twofold. Aspergillosis: 200mg once daily; average treatment duration 2～5 months. For invasive or disseminated disease, increase to 200mg twice daily. Candidiasis: 100～200mg once daily; average treatment duration 3 weeks～7 months. Cryptococcal meningitis: 200mg twice daily; average treatment duration 2 months～1 year. Maintenance therapy for cryptococcal meningitis: 200mg once daily. Paracoccidioidomycosis: 100mg once daily; average treatment duration 6 months.

This medication should be avoided in patients with impaired cardiac function. Care should be taken in patients with congestive heart failure or weak heart function when using this medication. Patients who have had allergic reactions to this medication or are sensitive to any of its ingredients should not use it. This medication interacts significantly with various drugs, so if you are taking other medications, consult your doctor or pharmacist. Serious side effects may occur if taken with certain medications. Women who are pregnant or potentially pregnant, as well as nursing mothers, should safely avoid using this medication. Patients with impaired liver or kidney function should be careful when using this medication, conducting regular tests on liver and kidney status. Rarely, this medication may cause severe liver damage, allergic reactions, heart problems, or neurological issues, so report any unusual symptoms to healthcare professionals immediately. Be cautious when driving or operating machinery as dizziness or vision abnormalities may occur. This medication may not be well absorbed in low-acid conditions, so taking it with acidic beverages when using antacids is advisable. In case of overdose, as there is no specific antidote, symptomatic treatment should be administered, and this medication is not removed by hemodialysis. Children and the elderly should use this medication with special caution, and safety in children has not been adequately established. This medication should be kept in its original container and stored out of reach of children.

Headache, nausea, abdominal pain, rhinitis, sinusitis, upper respiratory infection, leukopenia, hypersensitivity, taste disturbance, numbness, paresthesia, tinnitus, constipation, diarrhea, dyspepsia, bloating, vomiting, liver dysfunction, hyperbilirubinemia, itching, rash, hives, pollakiuria, erectile dysfunction, menstrual disorders, edema, neutropenia, thrombocytopenia, anaphylactoid reaction, hyperglycemia, hyperkalemia, hypokalemia, hypomagnesemia, confusion, peripheral neuropathy, dizziness, drowsiness, tremors, heart failure, left ventricular failure, tachycardia, hypertension, hypotension, pulmonary edema, voice disorder, cough, gastrointestinal disorders, liver failure, hepatitis, jaundice, erythematous rash, hyperhidrosis, myalgia, arthralgia, kidney dysfunction, urinary incontinence, generalized edema, facial swelling, chest pain, fever, pain, fatigue, chills, increased alanine aminotransferase, increased aspartate aminotransferase, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased blood urea, increased gamma-glutamyl transferase, elevated liver enzymes, abnormal urinalysis, leukocytosis, eosinophilia, anemia, vascular edema, serum sickness, angioedema, anaphylaxis, anaphylactic shock, allergic reactions, diplopia, visual impairment, hearing loss, ventricular extrasystole, atrioventricular block, palpitations, increased bowel movement, belching, glossitis, stomatitis, abdominal lumbar pain, pancreatitis, elevated serum total protein, elevated total bilirubin, increased LAP, decreased appetite, malaise, dark urine, mucocutaneous syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Lyell's syndrome, erythema multiforme, hair loss, photosensitivity reactions, exfoliative dermatitis, leukocytoclastic vasculitis, acute generalized exanthematous pustulosis, increased BUN, positive urine protein, positive urine glucose, decreased libido, drowsiness, shoulder stiffness, insomnia, chest pain, elevated serum triglycerides, flushing, elevated serum uric acid, elevated serum potassium, serum sickness, angioedema, anaphylactic reaction, hypertriglyceridemia, tremors, visual impairment, transient hearing loss, permanent hearing loss, congestive heart failure, dyspnea, significant hepatotoxicity, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, increased serum creatine kinase activity

This medication should be stored in a tightly sealed container to prevent air ingress and kept at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain its effectiveness and prevent degradation.

Appearance

White or pale yellow round film-coated tablet

Package unit

28 tablets/bottle, 100 tablets/bottle