Daewoong Bio Clarithromycin Tablets 250mg (Clarithromycin)

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: For 14 days, administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: Same as adults For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be administered to individuals with certain allergies. For instance, those who have previously shown allergic reactions to this drug or similar antibiotics should avoid use. Additionally, individuals with heart conditions or prior issues with heart rhythm need to be extra cautious when taking this medication, as there is a risk of irregular heartbeats. Patients with severely impaired liver or kidney function may require dosage adjustments and might need to avoid use in certain cases. It is safe for pregnant or nursing women to avoid this medication; if unavoidable, consultation with a healthcare professional is necessary. This medication may interact with several other drugs, so it is essential to inform your doctor or pharmacist of any other medications you are currently taking. Caution is especially needed when taken with heart-related medications, certain antibiotics, anticoagulants, and hypoglycemics. While taking this medication, rare allergic reactions or serious side effects may occur, and sudden shortness of breath, rashes, severe abdominal pain, diarrhea, or hearing loss should be immediately reported to medical personnel. For elderly patients or children, careful evaluation is necessary due to potential differences in physical function. Prolonged or repetitive use of this drug may lead to resistance, so adherence to the periods and dosages recommended by the physician is critical. Lastly, caution should be exercised during activities like driving or operating machinery, as dizziness or confusion may occur while taking this medication.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin erythema, angioedema, joint swelling, drug eruption, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral erosion, upper abdominal pain, thirst, transient teeth discoloration, pancreatitis, elevated amylase, dysgeusia, anorexia, constipation, fecal discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, chest X-ray abnormalities, eosinophilia, eosinophilic pulmonary infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, taste loss, olfactory loss, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, tremors, paresthesia, behavior changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular or cholestatic hepatitis, elevated liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, ageusia, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbances, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalised pustular psoriasis, muscle cramps, musculoskeletal stiffness, myopathy, elevated blood urea, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This medication is sensitive to light, so it should be stored in a special container that prevents light exposure. Moreover, it is important to maintain a storage temperature between 1 degree and 30 degrees Celsius to preserve its effectiveness and prevent degradation.

Appearance

Yellow rectangular film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle