Sconazole Tablets (Itraconazole)

Adult dosage

This medicine should preferably be administered immediately after meals to increase absorption. 1. Short-term treatment 1) Vulvovaginal candidiasis: Administer itraconazole 200 mg twice daily (morning and evening) for 1 day, or 200 mg once daily for 3 days. 2) Pityriasis versicolor: Administer 200 mg once daily for 7 days. 3) Tinea corporis, tinea cruris: Administer 100 mg once daily for 15 days. 4) Tinea manuum (interdigital), tinea pedis (interdigital): Administer 100 mg once daily for 15 days. 5) Tinea manuum (palmar), tinea pedis (plantar): Administer 100 mg once daily for 30 days, or 200 mg twice daily for 7 days. 6) Oropharyngeal candidiasis: Administer 100 mg once daily for 15 days. 7) Fungal keratitis: Administer 200 mg once daily for 21 days. 2. Onychomycosis 1) Pulse therapy Administer 200 mg twice daily for 1 week, followed by 3 weeks without treatment; this constitutes 1 cycle. Treat for up to 2 cycles if only the fingernails are infected, and up to 3 cycles if the toenails are infected. 2) Continuous therapy Administer 200 mg once daily for 3 months. The therapeutic effect continues for 3 months for fingernails and 6 months for toenails after the end of treatment. 3. Systemic fungal infections In patients with impaired immune function, such as those with neutropenia, AIDS, or organ transplant recipients, the oral bioavailability of this medicine may be reduced; therefore, double the dose if necessary. Aspergillosis: 200mg once daily for 2～5 months. For invasive or disseminated disease, increase to 200mg twice daily. Candidiasis: 100～200mg once daily for 3 weeks～7 months. Cryptococcal meningitis: 200mg twice daily for 2 months～1 year. Maintenance therapy: 200mg once daily. Paracoccidioidomycosis: 100mg once daily for 6 months.

This medication should not be used in patients with heart dysfunction, particularly those with congestive heart failure or a history of heart failure, unless in life-threatening infections. If symptoms of heart failure appear while taking this medication, it should be stopped immediately. Patients who are allergic to this medication or have hypersensitivity to its ingredients should not use it. Moreover, this medication can be dangerous when taken together with certain drugs, so it is necessary to verify if any other medications are being taken. Especially, co-administration with drugs that may affect heart rhythm or liver and kidney function is prohibited. It is safest for women who are pregnant or may become pregnant, as well as nursing mothers, not to take this medication. Patients with hereditary issues such as lactose intolerance should also refrain from taking this medication. Patients with impaired liver or kidney function should use this medication with caution and have regular liver function tests. Caution should also be exercised in patients with weakened immunity or those with certain neuropathies. While taking this medication, symptoms such as headache, nausea, and abdominal pain may occur, and rarely, abnormal liver function, skin rashes, or blood-related reactions can also occur. Consultation with healthcare professionals should be sought immediately if such symptoms appear. Caution is advised due to possible dizziness or visual disturbances while driving or operating machinery. This medication has many drug interactions, so it is essential to inform healthcare providers if other medications are being taken and to avoid taking prohibited combinations. When used with drugs that lower gastric acidity, the absorption of this medication may be reduced, and it is recommended to take it with acidic drinks. Pregnant or nursing women should avoid taking this medication, and women who may become pregnant should use effective contraception methods during and after taking this medication. There is no specific antidote for overdose, so it is crucial to receive treatment based on symptoms. Finally, this medication should be kept out of reach of children and stored in its original container.

Decreased myocardial contractility, headache, nausea, abdominal pain, rhinitis, sinusitis, upper respiratory infection, leukopenia, hypersensitivity, taste disturbance, sensory impairment, sensory abnormality, tinnitus, constipation, diarrhea, dyspepsia, abdominal distension, vomiting, liver dysfunction, hyperbilirubinemia, itching, rash, urticaria, polyuria, erectile dysfunction, menstrual disorders, edema, granulocytopenia, thrombocytopenia, anaphylactoid reaction, hyperglycemia, hyperkalemia, hypokalemia, hypomagnesemia, altered mental status, peripheral neuropathy, dizziness, drowsiness, tremor, heart failure, left ventricular failure, tachycardia, hypertension, hypotension, pulmonary edema, voice disorder, cough, gastrointestinal disturbance, liver failure, hepatitis, jaundice, erythematous rash, hyperhidrosis, myalgia, arthralgia, renal impairment, urinary incontinence, generalized edema, facial edema, chest pain, fever, pain, fatigue, chills, increased alanine aminotransferase, increased aspartate aminotransferase, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased blood urea nitrogen, increased gamma-glutamyl transferase, elevated liver enzymes, abnormal urinalysis, increased leukocytes, increased eosinophils, anemia, vascular edema, serum sickness, angioedema, anaphylaxis, anaphylactic shock, allergic reaction, diplopia, visual impairment, hearing loss, ventricular ectopic contraction, atrioventricular block, palpitations, increased intestinal motility, belching, glossitis, stomatitis, abdominal lumbar pain, pancreatitis, increased serum total protein, increased total bilirubin, increased LAP, loss of appetite, malaise, brown urine, mucocutaneous syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Riel syndrome, erythema multiforme, hair loss, photosensitivity reaction, exfoliative dermatitis, leukocyte destructive vasculitis, acute generalized exanthematous pustulosis, increased BUN, positive urine protein reaction, positive urine glucose reaction, decreased libido, drowsiness, malaise, shoulder stiffness, insomnia, chest pain, increased serum triglyceride levels, flushing, increased serum uric acid levels, increased serum potassium levels, serum sickness, angioedema, anaphylactic reaction, hypertriglyceridemia, tremor, visual impairment, hearing loss, congestive heart failure, dyspnea, pancreatitis, significant hepatotoxicity, toxic epidermal necrolysis, Steven-Johnson syndrome, acute generalized exanthematous pustulosis, erythema multiforme, exfoliative dermatitis, leukocyte destructive vasculitis, hair loss, photosensitivity, increased serum creatine phosphokinase

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, preferably at room temperature between 1 degree and 30 degrees Celsius. This storage method helps maintain the drug's efficacy and prevents degradation.

Appearance

White to pale white oval film-coated tablets

Package unit

30 tablets, 100 tablets