Lapezol Tablets 20mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: 10 mg orally once daily. Depending on symptoms, it can be increased to 20 mg orally once daily. For erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg orally once daily for 4 to 8 weeks; if symptoms do not resolve, it can be administered for an additional 8 weeks at 10 mg or 20 mg orally twice daily. However, the 20 mg dosage twice daily should be given only to patients with severe mucosal damage.

Child dose

Safety in pediatric patients has not been established.

This medication should not be used in patients with an allergy to specific ingredients or those who have experienced hypersensitivity to similar drugs previously. Pregnant or breastfeeding women should not take this medication. Caution is required when this medication is used in patients with poor liver function or the elderly, and if abnormal symptoms occur, immediate consultation with a healthcare provider is necessary. This medication may cause allergic reactions such as skin rash, itching, or hives; if such symptoms occur, use should be discontinued immediately. Regular blood tests are recommended as blood tests may show changes in red blood cells, white blood cells, or platelets. It may lead to liver function abnormalities, therefore liver enzyme levels should be checked periodically and if symptoms of hepatitis or jaundice occur, use should be discontinued immediately. Caution is required as it may affect heart and blood vessels, causing symptoms such as hypertension, palpitations, or arrhythmias. Various gastrointestinal symptoms such as diarrhea, abdominal pain, nausea, or vomiting may manifest and if abnormal symptoms persist, patients should notify their doctor. Neurological symptoms such as headache, dizziness, insomnia, or drowsiness may occur, so caution should be taken when driving or operating machinery. Respiratory symptoms such as cough or difficulty breathing may occur; if such symptoms arise, immediate consultation with healthcare staff is necessary. Muscle pain or joint pain may occur, so if symptoms are severe, it is advisable to inform healthcare providers. In case of severe rash or blisters on the skin, medication should be discontinued immediately and healthcare personnel informed, as there may be a rare occurrence of serious skin disorders. Abnormal eye symptoms or changes in vision may occur; if changes in sight are noted, an exam should be conducted. This medication may inhibit gastric acid secretion, increasing the risk of certain bacterial infections; hence, if diarrhea persists, healthcare personnel should be notified. Long-term use may increase the risk of bone fractures, so regular monitoring is necessary for those who use it for long periods under a doctor’s guidance. This medication may interact with other drugs, so if currently taking any medications, it is essential to inform your doctor or pharmacist. There is no specific antidote for overdose, and symptomatic treatment should be pursued immediately at a medical facility. This medication should not be chewed or crushed but swallowed whole, and kept out of reach of children.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweat
• paleness
• fulminant hepatitis
• liver function impairment
• jaundice
• angina pectoris

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechial hemorrhage

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. Furthermore, to maintain the effect of the medication, it is important to store it in a cool room temperature, specifically between 1°C and 30°C.

Appearance

Pale yellow round enteric-coated tablets

Package unit

28 tablets (14 tablets/PTP*2)